对小马重复注射大肠杆菌脂多糖的影响。
The effects of repeated administration of Escherichia coli lipopolysaccharides to ponies.
作者信息
Burrows G E
出版信息
Can J Comp Med. 1979 Jul;43(3):321-7.
Abstract
Repeated exposure of ponies in Escherichia coli endotoxin resulted in attenuation of the packed cell volume, beta-glucuronidase, capillary refill time and neutrophil responses usually accompanying endotoxin administration. An overall decrease in severity of clinical response including reduced mortality was also apparent in ponies with repeated endotoxin exposure. Modification of the febrile response was not observed in any of the experimental groups.
摘要
将小马反复暴露于大肠杆菌内毒素中，导致其红细胞压积、β-葡萄糖醛酸酶、毛细血管再充盈时间以及通常伴随内毒素给药出现的中性粒细胞反应减弱。在反复暴露于内毒素的小马中，临床反应严重程度的总体降低（包括死亡率降低）也很明显。在任何实验组中均未观察到发热反应的改变。
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