Alter M
Klinik für Dermatologie, Johannes-Wesling-Klinikum Minden, Universitätsklinik der Ruhr-Universität Bochum, 32429, Minden, Deutschland.
Dermatologie (Heidelb). 2024 Jun;75(6):497-506. doi: 10.1007/s00105-024-05321-y. Epub 2024 Mar 21.
Hidradenitis suppurativa (HS) is a chronic inflammatory skin and systemic disease that is associated with considerable discomfort and a significant reduction in the quality of life. Despite a significantly increased understanding of the disease, the diagnosis is still delayed for many years. Delayed patient access to suitable treatment often leads to disease progression with increased surgical interventions and the occurrence of possible comorbidities. In recent years, there has been an improved understanding of the pathophysiology and, as a result the authorization of modern therapeutic agents for HS. The treatment of HS is based on three treatment pillars: surgery, antibiotics and biologics. Additionally, risk factors, such as smoking and obesity should be positively influenced. Knowledge of comorbidities and their interdisciplinary treatment is important for the individualized care of patients.
化脓性汗腺炎（HS）是一种慢性炎症性皮肤和全身性疾病，会导致相当大的不适，并显著降低生活质量。尽管对该疾病的认识有了显著提高，但诊断仍会延迟多年。患者延迟获得合适的治疗往往会导致疾病进展，手术干预增加，并可能出现合并症。近年来，人们对病理生理学的认识有所提高，因此批准了用于HS的现代治疗药物。HS的治疗基于三个治疗支柱：手术、抗生素和生物制剂。此外，应积极改善吸烟和肥胖等风险因素。了解合并症及其跨学科治疗对患者的个体化护理很重要。
