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孕妇戒烟:一项随机对照试验,研究包括心率变异性生物反馈训练的电子健康干预措施的有效性。

Smoking cessation in pregnant women: A randomized controlled trial investigating the effectiveness of an eHealth intervention including heart rate variability-biofeedback training.

作者信息

van Dijk Willeke, Oosterman Mirjam, de Vente Wieke, Jansen Imke, Blankers Matthijs, Huizink Anja C

机构信息

Department of Clinical, Neuro and Developmental Psychology, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, van der Boechorststraat 7, 1081 BT Amsterdam, the Netherlands.

Department of Clinical Child and Family Studies, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, van der Boechorststraat 7, 1081 BT Amsterdam, the Netherlands.

出版信息

Addict Behav. 2024 Jul;154:108005. doi: 10.1016/j.addbeh.2024.108005. Epub 2024 Mar 2.

DOI:10.1016/j.addbeh.2024.108005
PMID:38513327
Abstract

BACKGROUND

Prenatal smoking and stress are associated with adverse health effects for women themselves and are risk factors for adverse outcomes of the child. Effective interventions are needed to support women with smoking cessation and reducing stress. The aims were (1) to test the effectiveness of an 8-week eHealth intervention targeting stress reduction and smoking cessation; (2) to examine whether stress reduction mediated the intervention effect on smoking behavior; (3) to test motivation to quit as a moderator; and (4) to investigate a dose-response effect of program usage.

METHODS

Pregnant women were included if they were >18 years of age, < 28 weeks pregnant at recruitment, and currently smoking. In total, 156 consenting participants were randomly assigned to the intervention or active control condition. Study outcomes on smoking (yes/no, frequency, and quantity) were collected via online questionnaires at pre-intervention (baseline; t0), post-intervention (8 weeks after t0; t1), and follow up at two weeks (t2) and three months (t3) after birth.

RESULTS

Smoking and stress reduced over the 8-week period in both conditions. The intervention effect on smoking was not mediated by stress reduction. Motivation to quit was found to moderate the intervention effect (smoking frequency and quantity) and a dose-response effect was found for program usage in the intervention for the reduction on smoking frequency and quantity.

CONCLUSION

Program usage and motivation to quit are important for smoking reduction in pregnant women. Further research is needed to examine how the intervention could be improved to increase treatment effectiveness.

摘要

背景

孕期吸烟和压力对女性自身的健康有不良影响,并且是儿童不良结局的危险因素。需要有效的干预措施来帮助女性戒烟并减轻压力。本研究的目的是:(1)测试一项为期8周的针对减轻压力和戒烟的电子健康干预措施的有效性;(2)研究压力减轻是否介导了干预对吸烟行为的影响;(3)测试戒烟动机作为调节因素的作用;(4)研究项目使用的剂量反应效应。

方法

纳入年龄大于18岁、招募时孕周小于28周且目前正在吸烟的孕妇。总共156名同意参与的参与者被随机分配到干预组或积极对照组。通过在线问卷在干预前(基线;t0)、干预后(t0后8周;t1)以及产后两周(t2)和三个月(t3)进行随访,收集吸烟情况(是/否、频率和数量)的研究结果。

结果

在两种情况下,吸烟和压力在8周内均有所降低。干预对吸烟的影响并未通过压力减轻来介导。发现戒烟动机调节了干预效果(吸烟频率和数量),并且在干预组中发现项目使用对吸烟频率和数量的降低存在剂量反应效应。

结论

项目使用和戒烟动机对孕妇减少吸烟很重要。需要进一步研究以探讨如何改进干预措施以提高治疗效果。

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