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Comment on "Effectiveness and safety of stem cell therapy for diabetic foot: a meta-analysis update".评论“干细胞治疗糖尿病足的有效性和安全性：荟萃分析更新”。
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本文引用的文献

1
Effectiveness and safety of stem cell therapy for diabetic foot: a meta-analysis update.干细胞治疗糖尿病足的有效性和安全性：荟萃分析更新。
Stem Cell Res Ther. 2022 Aug 13;13(1):416. doi: 10.1186/s13287-022-03110-9.
2
Protocol registration issues of systematic review and meta-analysis studies: a survey of global researchers.系统评价和荟萃分析研究的方案注册问题：全球研究人员的调查。
BMC Med Res Methodol. 2020 Aug 25;20(1):213. doi: 10.1186/s12874-020-01094-9.
3
Inclusion of zero total event trials in meta-analyses maintains analytic consistency and incorporates all available data.在荟萃分析中纳入零总事件试验可保持分析的一致性并纳入所有可用数据。
BMC Med Res Methodol. 2007 Jan 23;7:5. doi: 10.1186/1471-2288-7-5.

评论“干细胞治疗糖尿病足的有效性和安全性：荟萃分析更新”。

Comment on "Effectiveness and safety of stem cell therapy for diabetic foot: a meta-analysis update".

机构信息

Department of Cardiology, Longhua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Department of Nephrology A, Longhua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, China.

出版信息

Stem Cell Res Ther. 2024 Mar 21;15(1):85. doi: 10.1186/s13287-023-03608-w.

DOI:10.1186/s13287-023-03608-w
PMID:38515209
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10958930/
Abstract

In the study published by Sun et al., a systematic review and meta-analysis illustrated the advantageous of stem cell therapy in diabetic foot and can improve the quality of life of patients. Nevertheless, the authors had a lack of knowledge regarding the methodology of the meta-analysis, which had four main aspects: (1) The textual report is inconsistent with the forest plot results, i.e., the authors have insufficient knowledge of RevMan. (2) The "zero event" needs to be corrected for summary analysis. (3) Lack of aesthetics in the forest plots. (4) Registration is recommended for systematic reviews and meta-analyses.

摘要

在孙等人发表的研究中，系统评价和荟萃分析表明干细胞疗法在糖尿病足中的优势，可以提高患者的生活质量。然而，作者对荟萃分析的方法学缺乏了解，主要有四个方面：（1）文字报告与森林图结果不一致，即作者对 RevMan 的了解不足。（2）需要对汇总分析进行“零事件”校正。（3）森林图缺乏美感。（4）建议对系统评价和荟萃分析进行注册。