Hong Yinglu, Bao Dapeng, Manor Brad, Zhou Yuncong, Zhou Junhong
Beijing Sport University, School of Sport Medicine and Physical Therapy, Beijing, China.
Beijing Sport University, China Institute of Sport and Health Science, Beijing, China.
Neurophotonics. 2024 Jan;11(1):015009. doi: 10.1117/1.NPh.11.1.015009. Epub 2024 Mar 21.
Prefrontal cortex (PFC) hemodynamics are regulated by numerous underlying neurophysiological components over multiple temporal scales. The pattern of output signals, such as functional near-infrared spectroscopy fluctuations (i.e., fNIRS), is thus complex. We demonstrate first-of-its-kind evidence that this fNIRS complexity is a marker that captures the influence of endurance capacity and the effects of hydrogen gas () on PFC regulation.
We aim to explore the effects of different physical loads of exercise as well as the intaking of hydrogen gas on the fNIRS complexity of the PFC.
Twenty-four healthy young men completed endurance cycling exercise from 0 (i.e., baseline) to 100% of their physical loads after intaking 20 min of either or placebo gas (i.e., control) on each of two separate visits. The fNIRS measuring the PFC hemodynamics and heart rate (HR) was continuously recorded throughout the exercise. The fNIRS complexity was quantified using multiscale entropy.
The fNIRS complexity was significantly greater in the conditions from 25% to 100% of the physical load () compared with the baseline and after intaking before exercise; this increase of fNIRS complexity was significantly greater compared with the control (). At the baseline, participants with a greater fNIRS complexity had a lower HR (, ). Those with a greater increase of complexity had a lower increase of the HR (, ) during exercise.
These observations suggest that fNIRS complexity would be a marker that captures the adaptive capacity of PFC to endurance exercise and to the effects of interventions on PFC hemodynamics.
前额叶皮层（PFC）的血流动力学在多个时间尺度上受到众多潜在神经生理成分的调节。因此，诸如功能性近红外光谱波动（即fNIRS）等输出信号模式是复杂的。我们首次证明，这种fNIRS复杂性是一种标志物，可捕捉耐力能力的影响以及氢气（）对PFC调节的作用。
我们旨在探讨不同运动负荷以及摄入氢气对PFC的fNIRS复杂性的影响。
24名健康年轻男性在两次单独就诊时，每次在摄入20分钟的氢气或安慰剂气体（即对照）后，完成从0（即基线）到其身体负荷100%的耐力自行车运动。在整个运动过程中持续记录测量PFC血流动力学和心率（HR）的fNIRS。使用多尺度熵对fNIRS复杂性进行量化。
与基线相比，在身体负荷25%至100%（）的条件下以及运动前摄入氢气后，fNIRS复杂性显著更高；与对照（）相比，这种fNIRS复杂性的增加显著更大。在基线时，fNIRS复杂性较高的参与者心率较低（，）。在运动过程中，复杂性增加较大的参与者心率增加较低（，）。
这些观察结果表明，fNIRS复杂性将是一种标志物，可捕捉PFC对耐力运动以及对PFC血流动力学干预效果的适应能力。
