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澳大利亚一只德国牧羊犬出现的以脑室内出血为表现的播散性复杂感染。

Disseminated complex infection presenting as intraventricular brain hemorrhage in a German shepherd dog in Australia.

作者信息

Skinner Christopher, Allavena Rachel, Hoffmann Karon, Kelly-Bosma Mirrim, Kidd Sarah, Thomson Christine

机构信息

Animal Referral Hospital, 532 Seventeen Mile Rocks Road, Sinammon Park QLD 4073, Australia.

School of Veterinary Science, The University of Queensland, Gatton Campus, Gatton QLD 4343, Australia.

出版信息

Med Mycol Case Rep. 2024 Mar 8;44:100641. doi: 10.1016/j.mmcr.2024.100641. eCollection 2024 Jun.

DOI:10.1016/j.mmcr.2024.100641
PMID:38516609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10955049/
Abstract

A German Shepherd Dog diagnosed with based on fungal culture and DNA sequencing, is the first documented case in Australia, and the Southern Hemisphere. This species is part of complex, which is an emerging concern in immunocompromised human and veterinary patients. Intraventricular brain hemorrhage, noted on MRI, has not been reported previously in a dog with fungal encephalitis. The patient was euthanized due to progression of clinical signs before a final diagnosis was made, so no treatment was attempted in this case.

摘要

一只德国牧羊犬经真菌培养和DNA测序确诊感染,这是澳大利亚及南半球首例有记录的病例。该菌种是复合体的一部分,这在免疫功能低下的人类和兽医患者中是一个新出现的问题。磁共振成像(MRI)显示的脑室内出血,此前在患有真菌性脑炎的犬类中尚未有过报道。由于在做出最终诊断前临床症状进展,该患者被实施安乐死,因此本病例未尝试进行治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36e3/10955049/f6b2712d0a77/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36e3/10955049/7efa8b84e5c4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36e3/10955049/d04bcb58e57a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36e3/10955049/23032ddeaf11/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36e3/10955049/f6b2712d0a77/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36e3/10955049/7efa8b84e5c4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36e3/10955049/d04bcb58e57a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36e3/10955049/23032ddeaf11/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36e3/10955049/f6b2712d0a77/gr4.jpg

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本文引用的文献

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Disseminated Rasamsonia argillacea species complex infections in 8 dogs.8 只犬播散性 Rasamsonia argillacea 种复合体感染。
J Vet Intern Med. 2021 Sep;35(5):2232-2240. doi: 10.1111/jvim.16244. Epub 2021 Aug 13.
2
Systemic infection in a German shepherd cross dog.一只德国牧羊犬杂交犬的全身感染。
JMM Case Rep. 2017 Oct 18;4(10):e005125. doi: 10.1099/jmmcr.0.005125. eCollection 2017 Oct.
3
Long-Term Rasamsonia argillacea Complex Species Colonization Revealed by PCR Amplification of Repetitive DNA Sequences in Cystic Fibrosis Patients.
通过对囊性纤维化患者重复DNA序列进行PCR扩增揭示的长期阿吉拉罗萨菌属复合菌种定植情况
J Clin Microbiol. 2016 Nov;54(11):2804-2812. doi: 10.1128/JCM.01462-16. Epub 2016 Sep 7.
4
Disseminated Chrysosporium infection in a German shepherd dog.一只德国牧羊犬的播散性金孢子菌感染
Med Mycol Case Rep. 2016 Jan 23;10:29-33. doi: 10.1016/j.mmcr.2016.01.002. eCollection 2015 Dec.
5
Imaging characteristics of disseminated Geosmithia argillacea causing severe diskospondylitis and meningoencephalomyelitis in a dog.一株黏土嗜土丝孢菌引起犬严重椎间盘脊椎炎和脑膜脑脊髓炎的影像学特征
Clin Case Rep. 2015 Nov;3(11):901-6. doi: 10.1002/ccr3.372. Epub 2015 Sep 10.
6
First recovery of Rasamsonia argillacea species complex isolated in adolescent patient with cystic fibrosis in Slovenia--case report and review of literature.斯洛文尼亚首例从患有囊性纤维化的青少年患者中分离出的泥生拉氏菌物种复合体——病例报告及文献综述
Mycoses. 2015 Aug;58(8):506-10. doi: 10.1111/myc.12340. Epub 2015 Jun 9.
7
Validation of a novel real-time PCR for detecting Rasamsonia argillacea species complex in respiratory secretions from cystic fibrosis patients.一种用于检测囊性纤维化患者呼吸道分泌物中泥生拉氏菌物种复合体的新型实时PCR方法的验证。
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