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Homing and circulation of indium-111-labelled leucocytes. A post-mortem study.

作者信息

Signore A, Pozzilli C, Negri M, Lenzi G L, Pozzilli P

出版信息

Diagn Imaging Clin Med. 1985;54(6):315-7.

PMID:3851706
Abstract

The history of a patient with a suspected ischemic brain infarct undergoing an indium-111-tropolone white cell labelled test is reported. The patient, who died 12 h after injection of the labelled cells, suffered of a brain haemorrhage. The post-mortem examination has allowed for the first time the measurement of radioactivity in different organs following the injection of indium-111-labelled leucocytes. High radioactivity was found only in tissues affected by inflammatory processes and in the lymphonodes draining the corresponding areas. This report clearly indicates the importance of this method for the study of white cell localization and circulation to the sites of infections.

摘要

相似文献

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Guidelines for the labelling of leucocytes with (111)In-oxine. Inflammation/Infection Taskgroup of the European Association of Nuclear Medicine.用 (111)In-oxine 标记白细胞的指南。欧洲核医学协会炎症/感染工作组。
Eur J Nucl Med Mol Imaging. 2010 Apr;37(4):835-41. doi: 10.1007/s00259-010-1393-5.