沙特阿拉伯疫苗犹豫的潜在因素及其缓解措施：系统评价方案

Factors Underlying Vaccine Hesitancy and Their Mitigations in Saudi Arabia: Protocol for a Systematic Review.

作者信息

Kanan Mohammed, Abdulrahman Samar, Alshehri Abdulaziz, AlSuhaibani Renad, Alotaibi Nawaf M, Alsaleh Azhar, Nasser Bushra, Baowaydhan Rana, Alredaini Ibrahim, Khalid Taif, Almukhtar Fatima, Altoaimi Nourah, Alhneshel Almaha, Alanazi Shouq, Algmaizi Shahad

机构信息

Department of Clinical Pharmacy, King Fahad Medical City, Riyadh, Saudi Arabia.

Department of Pharmacy, Second Health Cluster, Riyadh, Saudi Arabia.

出版信息

JMIR Res Protoc. 2024 Mar 22;13:e54680. doi: 10.2196/54680.

DOI:10.2196/54680

PMID:38517463

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10998176/

Abstract

BACKGROUND

Vaccine hesitancy is a growing concern in Saudi Arabia, impacting even well-educated parents. The decision-making process involves various factors such as accessibility, trustworthy information, and the influence of social networks, reflecting a complex interplay of emotional, cultural, social, spiritual, and political dimensions.

OBJECTIVE

This review seeks to evaluate the prevalence and trends of vaccine hesitancy, identify contributing factors, and explore potential solutions to enhance immunization rates. This review aligns with global concerns, as the World Health Organization has identified vaccine hesitancy as a top global health threat.

METHODS

Our systematic review will follow the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and PICOS (Population, Intervention, Comparison, Outcomes, and Study) criteria for comprehensive assessment. We will conduct a thorough search across various databases, encompassing a wide range of vaccines, and pay special attention to vaccination campaigns and refusals. Inclusion criteria involve descriptive, observational, and analytical studies focusing on factors influencing vaccine acceptance or hesitancy. The study will use the Crowe Critical Appraisal Tool for quality assessment and perform a narrative synthesis to summarize findings thematically.

RESULTS

This systematic review is expected to unveil the prevalence and trends of vaccine hesitancy in diverse populations in Saudi Arabia, shedding light on cultural, religious, and social factors contributing to hesitancy. It aims to assess the effectiveness of implemented strategies, enable regional and global comparisons, and provide implications for tailored vaccination policies. Additionally, the review may pinpoint research gaps, guiding future investigations to address and mitigate vaccine hesitancy effectively.

CONCLUSIONS

The findings are expected to have direct policy implications and guide interventions to strengthen vaccination programs and improve public health outcomes.

INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/54680.

摘要

背景

疫苗犹豫在沙特阿拉伯日益受到关注，甚至影响到受过良好教育的父母。决策过程涉及多种因素，如可及性、可靠信息以及社交网络的影响，反映出情感、文化、社会、精神和政治层面的复杂相互作用。

目的

本综述旨在评估疫苗犹豫的患病率和趋势，确定促成因素，并探索提高免疫接种率的潜在解决方案。由于世界卫生组织已将疫苗犹豫确定为全球首要的健康威胁，因此本综述与全球关注的问题相一致。

方法

我们的系统综述将遵循PRISMA（系统评价和Meta分析的首选报告项目）指南和PICOS（人群、干预措施、对照、结局和研究）标准进行全面评估。我们将在各种数据库中进行全面搜索，涵盖广泛的疫苗，并特别关注疫苗接种活动和拒绝接种情况。纳入标准包括侧重于影响疫苗接受或犹豫因素的描述性、观察性和分析性研究。该研究将使用克劳批判性评估工具进行质量评估，并进行叙述性综合以按主题总结研究结果。