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沙特阿拉伯奈季兰地区父母的态度、他们对儿童新冠疫苗的接受情况及影响因素:一项横断面调查

Parents'Attitudes, Their Acceptance of the COVID-19 Vaccines for Children and the Contributing Factors in Najran, Saudi Arabia: A Cross-Sectional Survey.

作者信息

Aedh Abdullah Ibrahim

机构信息

Department of Internal Medicine, College of Medicine, Najran University, Najran 1988, Saudi Arabia.

出版信息

Vaccines (Basel). 2022 Aug 6;10(8):1264. doi: 10.3390/vaccines10081264.

DOI:10.3390/vaccines10081264
PMID:36016152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9414087/
Abstract

BACKGROUND

The COVID-19 pandemic is still ongoing, so it is critical to immunize the majority of people, including children, to achieve herd immunity against the pandemic. As parents are the ones who ultimately decide whether or not to vaccinate their children, this study was conducted to determine parental acceptance and hesitancy toward vaccinating their children against COVID-19, as well as their knowledge of and concerns regarding vaccination against COVID-19, as well as factors that might influence their willingness to vaccinate in Najran city, Saudi Arabia.

METHODS

In February 2022, a cross-sectional, questionnaire-based study using a convenientand snowball sampling technique was carried out. Parents of children between the ages of 5 and 11 were given access to an online self-administered survey. The poll was, however, open to parents of children under the age of 5. Using the Raosoft sample size calculator, the minimum necessary sample size was determined to be 384 under the assumptions of a 5% margin of error and a 95% confidence level. A value of less than 0.05 was deemed significant for the statistical analysis, which was carried out using SPSS version 27. To examine the relationship between demographic factors and how drivers affect parents' willingness to vaccinate their children against COVID-19, a chi-square test was performed. Through multivariate regression analysis, the predictors of vaccine hesitancy were identified.

RESULTS

A total of 464 responses were collected and subjected to data analysis. More than half of the parents were male (56.9%) and between the ages of 26 and 40 (56.7%). Most parents have children aged between 5-11 years (73.5%). Of parents, 72.2% showed vaccine hesitancy and were 9.5 times less likely to immunize their children against COVID-19. About 27.8% of the parents were ready to vaccinate their children against COVID-19 as soon as possible, compared to 15.51% of parents who were not at all interested in vaccinating their children. Parents under 25 (34.48%) and over 41 (37.79%), non-Saudi (40.59%), holding postgraduate and higher degrees (39.5%), earning more than 10,000 SAR per month (34.96%), working as healthcare professionals (40.36%) and in government sectors (33.93%), self-employed (33.33%), with three to five children (35.26%) and male (31.33%) demonstrated significantly high willingness to vaccinate their children against the COVID-19 vaccine compared to their counterparts. Parents who concur that COVID-19 vaccination may have serious adverse effects in children, who believe that COVID-19 is an uncommon disease and does not require vaccination, have had a family member infected withCOVID-19 with severe symptoms, who were unvaccinated and had severe to moderate symptoms after vaccination, showed significantly higher unwillingness to vaccinate their children against COVID-19. Parents who take safety precautions and do not believe that new vaccines provide an increased risk had higher vaccination intentions for their children. A positive impact of mandatory childhood vaccination was noted on the COVID-19 vaccination. Parents with children suffering from any chronic disease exhibited a 9.9 times higher hesitancy to vaccinate their children against COVID-19. A total of 47.8% of parents had come across or heard about anti-COVID-19 vaccination campaigns. A lack of adequate safety data, potential future consequences, and vaccine efficacy were the main concerns with COVID-19 vaccines. The primary information source for COVID-19-related information was the Saudi Ministry of Health (MOH).

CONCLUSIONS

Parents' hesitation to get the COVID-19 vaccine at a significant rate may compromise the success of the ongoing vaccination campaign. The development and implementation of multi-component interventions are required. Hospital- and community-based programs must be used to get in touch with parents.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32a6/9414087/567ae2dd3157/vaccines-10-01264-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32a6/9414087/e096a83b5f38/vaccines-10-01264-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32a6/9414087/5667abfaf7ef/vaccines-10-01264-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32a6/9414087/567ae2dd3157/vaccines-10-01264-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32a6/9414087/e096a83b5f38/vaccines-10-01264-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32a6/9414087/5667abfaf7ef/vaccines-10-01264-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32a6/9414087/567ae2dd3157/vaccines-10-01264-g003.jpg
摘要

背景

新冠疫情仍在持续,因此为包括儿童在内的大多数人接种疫苗以实现群体免疫至关重要。由于最终决定是否为孩子接种疫苗的是家长,本研究旨在确定沙特阿拉伯奈季兰市家长对为孩子接种新冠疫苗的接受度和犹豫程度,以及他们对新冠疫苗接种的了解和担忧,还有可能影响其接种意愿的因素。

方法

2022年2月,采用便利抽样和滚雪球抽样技术开展了一项基于问卷调查的横断面研究。5至11岁儿童的家长可参与在线自填式调查。不过,该调查也向5岁以下儿童的家长开放。使用Raosoft样本量计算器,在误差幅度为5%、置信水平为95%的假设下,确定所需最小样本量为384。使用SPSS 27版进行统计分析,p值小于0.05被视为具有统计学意义。为检验人口统计学因素与驱动因素如何影响家长为孩子接种新冠疫苗的意愿之间的关系,进行了卡方检验。通过多变量回归分析确定了疫苗犹豫的预测因素。

结果

共收集到464份回复并进行数据分析。超过一半的家长为男性(56.9%),年龄在26至40岁之间(56.7%)。大多数家长的孩子年龄在5至11岁之间(73.5%)。72.2%的家长表现出疫苗犹豫,为孩子接种新冠疫苗的可能性比其他家长低9.5倍。约27.8%的家长准备尽快为孩子接种新冠疫苗,相比之下,15.51%的家长对为孩子接种疫苗完全不感兴趣。25岁以下(34.48%)和41岁以上(37.79%)家长、非沙特人(40.59%)、拥有研究生及以上学历(39.5%)、月收入超过10000沙特里亚尔(34.96%)、从事医疗保健专业工作(40.36%)和在政府部门工作(33.93%)、自营职业(33.33%)、育有三至五个孩子(35.26%)以及男性(31.33%)的家长,相比其他家长,为孩子接种新冠疫苗的意愿显著更高。认为新冠疫苗接种可能对儿童产生严重不良反应、认为新冠是罕见疾病无需接种疫苗、有家庭成员感染新冠且症状严重、未接种疫苗且接种后出现严重至中度症状的家长,为孩子接种新冠疫苗的意愿明显更低。采取安全预防措施且不认为新疫苗会增加风险的家长,为孩子接种疫苗的意愿更高。注意到儿童强制接种疫苗对新冠疫苗接种有积极影响。孩子患有任何慢性病的家长,为孩子接种新冠疫苗的犹豫程度高出9.9倍。共有47.8%的家长遇到或听说过新冠疫苗接种活动。对新冠疫苗的主要担忧是缺乏足够的安全数据、潜在的未来后果和疫苗效力。新冠相关信息的主要来源是沙特卫生部。

结论

家长在很大程度上对新冠疫苗犹豫不决,可能会影响正在进行的疫苗接种活动的成功。需要制定和实施多方面的干预措施。必须利用基于医院和社区的项目与家长取得联系。

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