Cardiovascular MRI Laboratory, Division of Cardiovascular Imaging, Houston Methodist DeBakey Heart & Vascular Center, Weill Cornell Medical College, 6550 Fannin Street, Smith Tower - Suite 1801, Houston, TX, 77030, USA.
Curr Cardiol Rep. 2024 May;26(5):413-421. doi: 10.1007/s11886-024-02044-3. Epub 2024 Mar 22.
Cardiac magnetic resonance (CMR) is emerging as a valuable imaging modality for the assessment of aortic regurgitation (AR). In this review, we discuss the assessment of AR severity, left ventricular (LV) remodeling, and tissue characterization by CMR while highlighting the latest studies and addressing future research needs.
Recent studies have further established CMR-based thresholds of AR severity and LV remodeling that are associated with adverse clinical outcomes, and lower than current guideline criteria. In addition, tissue profiling with late gadolinium enhancement (LGE) and extracellular volume (ECV) quantification can reliably assess adverse myocardial tissue remodeling which is also associated with adverse outcomes. The strengths and reproducibility of CMR in evaluating ventricular volumes, tissue characteristics, and regurgitation severity position it as an excellent modality in evaluating and following AR patients. Advanced CMR techniques for the detection of tissue remodeling have shown significant potential and merit further investigation.
心脏磁共振（CMR）作为一种评估主动脉瓣反流（AR）的有价值的成像方式正在兴起。在这篇综述中，我们讨论了 CMR 评估 AR 严重程度、左心室（LV）重构和组织特征的方法，同时强调了最新的研究成果并探讨了未来的研究需求。
最近的研究进一步确定了基于 CMR 的 AR 严重程度和 LV 重构的阈值，这些阈值与不良临床结局相关，且低于目前的指南标准。此外，通过钆延迟增强（LGE）和细胞外容积（ECV）定量进行组织分析可以可靠地评估不良心肌组织重构，这也与不良结局相关。CMR 在评估心室容积、组织特征和反流严重程度方面的优势和可重复性使其成为评估和随访 AR 患者的理想方式。用于检测组织重构的先进 CMR 技术显示出了巨大的潜力，值得进一步研究。
