Kobashi H, Nishioka A, Miyamoto N, Oohara K, Okamoto T
Jpn J Antibiot. 1985 Jul;38(7):1911-7.
Aspoxicillin (TA-058, ASPC) was given intravenously to 20 children with the following acute bacterial infections; 11 cases of bronchopneumonia, 5 cases of urinary tract infection, 2 cases of acute bronchitis, 1 case of staphylococcal scalded skin syndrome and 1 case of subcutaneous abscess. Clinical effectiveness was obtained in 14 cases out of 20 cases (70%) and bacteriological eradication in 8 cases out of 10 cases (80%). With ASPC the following side effects developed; transient diarrhea in 1 case, eruption in 1 case and slight elevation of GOT in 1 case. From the above clinical results, it is apparent that ASPC is an useful antibiotic for treating pediatric patients with various kinds of bacterial infections.
将阿扑西林（TA - 058，ASPC）静脉注射给20名患有以下急性细菌感染的儿童；11例支气管肺炎、5例尿路感染、2例急性支气管炎、1例葡萄球菌烫伤样皮肤综合征和1例皮下脓肿。20例中有14例（70%）获得临床疗效，10例中有8例（80%）细菌学清除。使用ASPC出现了以下副作用；1例出现短暂腹泻，1例出现皮疹，1例谷草转氨酶轻度升高。从上述临床结果来看，很明显ASPC是治疗患有各种细菌感染的儿科患者的一种有用抗生素。
