Kobashi H, Aihara R, Nishioka A, Oohara K, Okamoto T
Jpn J Antibiot. 1985 Nov;38(11):3316-22.
Aztreonam (AZT) was given intravenously to 20 children with the following acute bacterial infections: 13 cases of bronchopneumonia, 5 cases of urinary tract infection, 1 case of cervical lymphadenitis with acute tonsillitis and 1 case of acute enteritis. Clinical effectiveness was obtained in 17 cases of 20 cases and bacteriological effectiveness in 10 strains out of 11 strains. No side effect was observed except for 2 cases with eruption, 1 case with slight elevation of GPT, 1 case with slight elevation of GOT and 1 case with slight elevation of GOT and GPT. From the above clinical results, it is apparent that AZT is a useful antibiotic for treating pediatric patients with various kinds of bacterial infections.
氨曲南（AZT）静脉注射给药于20例患有以下急性细菌感染的儿童：13例支气管肺炎、5例尿路感染、1例伴有急性扁桃体炎的颈部淋巴结炎和1例急性肠炎。20例中有17例获得临床疗效，11株菌株中有10株获得细菌学疗效。除2例出现皮疹、1例谷丙转氨酶（GPT）轻度升高、1例谷草转氨酶（GOT）轻度升高以及1例GOT和GPT轻度升高外，未观察到副作用。从上述临床结果来看，显然氨曲南是治疗患有各种细菌感染的儿科患者的一种有用抗生素。
