Faculty of Sports and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.
Institut de Cardiologie de Montréal, Montréal, QC, Canada.
Physiol Rep. 2024 Mar;12(6):e15986. doi: 10.14814/phy2.15986.
Cardiovascular and mental diseases are among the most important global health problems, but little is known on the associations between mental and arterial health in adolescents. Therefore, we investigated the associations of arterial health with depressive symptoms and perceived stress in adolescents. A total of 277 adolescents, 151 boys, 126 girls, aged 15-17 years participated in the study. Depressive symptoms were assessed using the Beck Depression Inventory and perceived stress by the Cohen Perceived Stress Scale. Arterial health was assessed by measures from carotid ultrasonography (carotid intima-media thickness, Young's Elastic Modulus, carotid artery distensibility, stiffness index), impedance cardiography (pulse wave velocity, cardio-ankle vascular index), and pulse contour analysis (reflection index, stiffness index). The data were analyzed using linear regression models adjusted for age and sex. Depressive symptoms or perceived stress were not associated with indices of arterial health in the whole study group (β = -0.08 to 0.09, p > 0.05), in boys (β = -0.13 to 0.10, p > 0.05) or in girls (standardized regression coefficient β = -0.16 to 0.08, p > 0.05). We found no associations of depressive symptoms and perceived stress with arterial health in adolescents. These observations suggest that the association between mental and arterial health problems develop in later life.
心血管疾病和精神疾病是全球最重要的健康问题之一，但人们对青少年的精神和动脉健康之间的关系知之甚少。因此，我们研究了青少年的动脉健康与抑郁症状和感知压力之间的关系。共有 277 名年龄在 15 至 17 岁的青少年（151 名男孩，126 名女孩）参加了这项研究。抑郁症状使用贝克抑郁量表评估，感知压力使用科恩感知压力量表评估。动脉健康通过颈动脉超声（颈动脉内膜中层厚度、杨氏弹性模量、颈动脉可扩张性、僵硬指数）、阻抗心动图（脉搏波速度、心踝血管指数）和脉搏轮廓分析（反射指数、僵硬指数）进行评估。使用线性回归模型对年龄和性别进行调整后分析数据。在整个研究组（β=-0.08 至 0.09，p>0.05）、男孩（β=-0.13 至 0.10，p>0.05）或女孩（标准化回归系数β=-0.16 至 0.08，p>0.05）中，抑郁症状或感知压力与动脉健康指数均无关联。这些发现表明，精神和动脉健康问题之间的关联是在以后的生活中发展起来的。
