López-González Ángel Arturo, Martínez-Almoyna Rifá Emilio, Oliveira Hernán Paublini, Sánchez Cristina Martorell, Tárraga López Pedro Juan, Ramírez-Manent José Ignacio
ADEMA-Health Group of University Institute of Health Sciences (IUNICS) of Balearic Islands, 07120 Palma, Spain.
Faculty of Odontology, University School ADEMA-UIB, 07009 Palma, Spain.
Life (Basel). 2025 Jan 16;15(1):116. doi: 10.3390/life15010116.
Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most common cause of chronic liver disease worldwide, with a multifactorial etiology. This study aims to evaluate the associations between various sociodemographic variables, healthy habits, and stress with risk scale values for MAFLD.
A descriptive, cross-sectional study was conducted on 16,708 Spanish workers to assess how sociodemographic variables (age, gender, and socioeconomic status), healthy habits (smoking, Mediterranean diet adherence, and physical activity), and stress correlate with values from three MAFLD risk scales: fatty liver index (FLI), hepatic steatosis index (HSI), and lipid accumulation product (LAP).
All analyzed variables were associated with the values of the three MAFLD risk scales. Among them, the variables showing the strongest associations (represented by odds ratio values) were age and physical activity.
The profile of an individual at higher risk of elevated MAFLD risk scale values is a male, aged 50 or older, belonging to lower socioeconomic levels (manual laborers), a smoker, sedentary, with low adherence to the Mediterranean diet, and with high stress scale scores.
代谢功能障碍相关脂肪性肝病(MAFLD)是全球慢性肝病最常见的病因,其病因具有多因素性。本研究旨在评估各种社会人口统计学变量、健康习惯和压力与MAFLD风险量表值之间的关联。
对16708名西班牙工人进行了一项描述性横断面研究,以评估社会人口统计学变量(年龄、性别和社会经济地位)、健康习惯(吸烟、地中海饮食依从性和体育活动)以及压力如何与三种MAFLD风险量表的值相关:脂肪肝指数(FLI)、肝脂肪变性指数(HSI)和脂质蓄积产物(LAP)。
所有分析变量均与三种MAFLD风险量表的值相关。其中,关联最强的变量(以比值比表示)是年龄和体育活动。
MAFLD风险量表值升高风险较高的个体特征为男性,年龄在50岁及以上,社会经济水平较低(体力劳动者),吸烟者,久坐不动,地中海饮食依从性低,压力量表得分高。