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Measurable residual disease quantification in adult patients with KMT2A-rearranged acute lymphoblastic leukemia.

作者信息

Burmeister Thomas, Ströh Aeint-Steffen, Kehden Britta, Trautmann Heiko, Meyer Claus, Marschalek Rolf, Larghero Patrizia, Schwartz Stefan, Steffen Björn, Spriewald Bernd, Heinicke Thomas, Jäkel Nadja, Westermann Jörg, Nachtkamp Kathrin, Viardot Andreas, Topp Max S, Neumann Martin, Baldus Claudia D, Gökbuget Nicola, Brüggemann Monika

机构信息

Department of Hematology, Oncology and Tumor Immunology, CVK, Charité-Universitätsmedizin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

University Cancer Center Schleswig-Holstein (UCCSH), University Hospital Schleswig-Holstein, Kiel, Germany.

出版信息

Leukemia. 2024 Jul;38(7):1600-1603. doi: 10.1038/s41375-024-02209-7. Epub 2024 Mar 22.

DOI:10.1038/s41375-024-02209-7
PMID:38519799
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11216977/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2090/11216977/3ae007e532da/41375_2024_2209_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2090/11216977/b5022ad7c81e/41375_2024_2209_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2090/11216977/3ae007e532da/41375_2024_2209_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2090/11216977/b5022ad7c81e/41375_2024_2209_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2090/11216977/3ae007e532da/41375_2024_2209_Fig2_HTML.jpg

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本文引用的文献

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Genetic alterations and MRD refine risk assessment for KMT2A-rearranged B-cell precursor ALL in adults: a GRAALL study.基因改变和微小残留病优化成人KMT2A重排B细胞前体急性淋巴细胞白血病的风险评估:一项GRAALL研究
Blood. 2023 Nov 23;142(21):1806-1817. doi: 10.1182/blood.2023021501.
2
MRD in adult Ph/BCR-ABL-negative ALL: how best to eradicate?成人 Ph/BCR-ABL 阴性 ALL 中的微小残留病灶:如何最好地清除?
Hematology Am Soc Hematol Educ Program. 2021 Dec 10;2021(1):718-725. doi: 10.1182/hematology.2021000224.
3
Clinical Implications of Minimal Residual Disease Detection in Infants With -Rearranged Acute Lymphoblastic Leukemia Treated on the Interfant-06 Protocol.
《基于 Interfant-06 方案治疗伴有 - 重现性急性淋巴细胞白血病婴儿患者中微小残留病灶检测的临床意义》。
J Clin Oncol. 2021 Feb 20;39(6):652-662. doi: 10.1200/JCO.20.02333. Epub 2021 Jan 6.
4
Minimal residual disease diagnostics in acute lymphoblastic leukemia: need for sensitive, fast, and standardized technologies.急性淋巴细胞白血病中的微小残留病诊断:对灵敏、快速且标准化技术的需求。
Blood. 2015 Jun 25;125(26):3996-4009. doi: 10.1182/blood-2015-03-580027. Epub 2015 May 21.
5
The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias.婴儿MLL重排急性淋巴细胞白血病的体细胞突变图谱。
Nat Genet. 2015 Apr;47(4):330-7. doi: 10.1038/ng.3230. Epub 2015 Mar 2.
6
Identification of CD34+ and CD34- leukemia-initiating cells in MLL-rearranged human acute lymphoblastic leukemia.在MLL重排的人类急性淋巴细胞白血病中鉴定CD34 +和CD34 -白血病起始细胞。
Blood. 2015 Feb 5;125(6):967-80. doi: 10.1182/blood-2014-03-563304. Epub 2014 Dec 23.
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Oncogenetics and minimal residual disease are independent outcome predictors in adult patients with acute lymphoblastic leukemia.在成人急性淋巴细胞白血病患者中,oncogenetics 和微小残留病是独立的预后预测因素。
Blood. 2014 Jun 12;123(24):3739-49. doi: 10.1182/blood-2014-01-547695. Epub 2014 Apr 16.
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Adult patients with acute lymphoblastic leukemia and molecular failure display a poor prognosis and are candidates for stem cell transplantation and targeted therapies.急性淋巴细胞白血病伴分子学复发的成年患者预后不良,是干细胞移植和靶向治疗的候选人群。
Blood. 2012 Aug 30;120(9):1868-76. doi: 10.1182/blood-2011-09-377713. Epub 2012 Mar 22.
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The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: results from the GMALL study group.成人CD10阴性B细胞前体急性淋巴细胞白血病的MLL重组组:来自GMALL研究组的结果。
Blood. 2009 Apr 23;113(17):4011-5. doi: 10.1182/blood-2008-10-183483. Epub 2009 Jan 14.