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基础科学的未来:女性盆底医学新一代机制研究人员的发展。

The Future of Basic Science: Development of the Next Generation of Mechanistic Researchers in Female Pelvic Medicine.

机构信息

Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Urogynecology and Pelvic Reconstructive Surgery, University of California, San Diego, San Diego, CA, 92037, USA.

Sanford Consortium for Regenerative Medicine, La Jolla, CA, 92037, USA.

出版信息

Int Urogynecol J. 2024 Apr;35(4):775-779. doi: 10.1007/s00192-024-05766-8. Epub 2024 Mar 25.

Abstract

INTRODUCTION AND HYPOTHESIS

The International Urogynecological Association (IUGA) brought together senior and junior members actively engaged in scholarly and educational activities for a consensus conference centered on developing a strategy for sustainable training of the next generation of mechanistic researchers in female pelvic medicine.

METHODS

Four a priori identified major foci were explored in a half-day virtual consensus conference. Participants included representatives from various countries and disciplines with diverse backgrounds-clinicians, physician-scientists, and basic scientists in the fields of urogynecology, biomechanical engineering, and molecular biology. Following a keynote address, each focus area was first tackled by a dedicated breakout group, led by the Chair(s) of the most relevant IUGA committees. The break-out sessions were followed by an iterative discussion among all attendees to identify mitigating strategies to address the shortage of mechanistic researchers in the field of female pelvic medicine.

RESULTS

The major focus areas included: research priorities for IUGA basic science scholar program; viable strategies for sustainable basic science mentorship; core competencies in basic science training; and the challenges of conducting complex mechanistic experiments in low-resource countries. Key gaps in knowledge and core competencies that should be incorporated into fellowship/graduate training were identified, and existing training modalities were discussed. Recommendations were made for pragmatic approaches to increasing the exposure of trainees to learning tools to enable sustainable training of the next generation of basic science researchers in female pelvic medicine worldwide.

CONCLUSIONS

The attendees presented multiple perspectives to gain consensus regarding critical areas of need for training future generations of mechanistic researchers. Recommendations for a sustainable Basic Science Scholar Program were developed using IUGA as a platform. The overarching goal of such a program is to ensure a successful bench-to-bedside-and-back circuit in Urogynecology and Pelvic Reconstructive Surgery, ultimately improving lives of millions of women worldwide through scientifically rational effective preventative and therapeutic interventions.

摘要

简介与假设

国际尿妇科协会(IUGA)召集了资深和初级成员,他们积极参与学术和教育活动,召开了一次共识会议,重点是制定一项战略,为女性盆底医学领域下一代机械研究人员的可持续培训提供支持。

方法

在为期半天的虚拟共识会议上,探讨了四个预先确定的主要焦点。参与者包括来自不同国家和学科的代表,他们具有不同的背景——临床医生、医师科学家以及泌尿妇科、生物力学工程和分子生物学领域的基础科学家。在主旨演讲之后,每个重点领域首先由相关 IUGA 委员会的主席领导的专门分组进行讨论。分组讨论之后,所有与会者进行了迭代讨论,以确定缓解策略,解决女性盆底医学领域机械研究人员短缺的问题。

结果

主要重点领域包括:IUGA 基础科学学者计划的研究重点;可持续基础科学指导的可行策略;基础科学培训的核心能力;以及在资源匮乏国家开展复杂机械实验的挑战。确定了应纳入奖学金/研究生培训的知识和核心能力方面的关键差距,并讨论了现有的培训模式。提出了切实可行的方法建议,以增加学员接触学习工具的机会,从而在全球范围内为女性盆底医学领域的下一代基础科学研究人员提供可持续的培训。

结论

与会者提出了多种观点,以就培训未来几代机械研究人员的关键需求领域达成共识。使用 IUGA 作为平台,制定了可持续基础科学学者计划的建议。该计划的总体目标是确保泌尿妇科和盆底重建手术的从基础到临床再回到基础的成功循环,最终通过科学合理的有效预防和治疗干预措施,改善全球数百万女性的生活。

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