Ikrou H, Salek M, Boustani S, Bouissar W, Wakrim S, Abdala S, Serhane H
Pulmonology Department, CHR HASSAN II, CHU Souss-Massa, Laboratory LARISS, FMPA, UIZ - Agadir, Morocco.
Radiology Department, CHR HASSAN 2, CHU SOUSS MASSA, FMPA, Agadir, Morocco.
Radiol Case Rep. 2024 Mar 16;19(6):2218-2223. doi: 10.1016/j.radcr.2024.02.036. eCollection 2024 Jun.
Rheumatoid arthritis (RA) is one of the most common types of autoimmune arthritis. It can also involve other organs, including vascular structures, and lungs which are affected in 60% to 80% of cases. Other complications may present as airway infections and drug related pulmonary toxicity. We present the case of 75-year-old male patient of North African decent that was hospitalized initially for chronic dyspnea associated with other systemic manifestations, and in whom we confirmed the diagnosis of Rheumatoid arthritis associated interstitial lung disease. The patient was treated with methotrexate (MTX) and later on, he developed a fatal case of methotrexate related pulmonary toxicity.
类风湿关节炎（RA）是最常见的自身免疫性关节炎类型之一。它还可累及其他器官，包括血管结构，60%至80%的病例肺部会受到影响。其他并发症可能表现为气道感染和药物相关的肺毒性。我们报告了一例75岁的北非裔男性患者，他最初因慢性呼吸困难及其他全身表现住院，我们确诊其患有类风湿关节炎相关间质性肺病。该患者接受了甲氨蝶呤（MTX）治疗，后来，他发生了一例致命的甲氨蝶呤相关肺毒性病例。
