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光生物调节疗法在治疗因牙龈乳头缺失导致的“黑三角”中的应用

Photobiomodulation Therapy in the Management of "Black Triangles" Due to the Absence of the Gingival Interdental Papilla.

作者信息

El Mobadder Marwan, Nammour Samir

机构信息

Department of Dental Sciences, University of Liege, Faculty of Medicine, Liege, BEL.

出版信息

Cureus. 2024 Feb 22;16(2):e54682. doi: 10.7759/cureus.54682. eCollection 2024 Feb.

DOI:10.7759/cureus.54682
PMID:38524013
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10960618/
Abstract

The absence of an interdental papilla, termed "black triangle," presents a challenge in aesthetic restorations. Photobiomodulation therapy (PBMT) is the non-thermal therapeutic use of light in order to positively modulate biological activity and has shown promise in tissue regeneration, wound healing, and inflammation reduction. This case report introduces a modified PBM protocol known as "hemolasertherapy" aimed at regenerating the gingival interdental papilla to fill the black triangle. In this case report, a 34-year-old female with an unaesthetic black triangle between the maxillary central incisors presented for treatment. Before surgical intervention, our suggested protocol was proposed and explained, detailing potential risks and outcomes. After proper scaling root planning, a suggested protocol with PBM was made. PBM application with a 635 nm wavelength diode laser at four points around the area between the two maxillary central incisors was made: coronal third and apical third of the papilla and mesial and distal of the papilla. Then, bleeding was provoked with a curette inside the sulcus between 11 and 21 (concerned area) by applying pressure on the junctional epithelium and the supracrestal connective tissue. After a few seconds, blood spontaneously filled the "black triangle" coronal to the interdental papilla and was left undisturbed. At this point, PBM was applied again on the same four points already described. The irradiation parameters during all PBM treatments were contact mode and continuous mode, 635 nm wavelength, spot size of 8mm power of 50 mW, irradiation time on each point of 50 seconds, and energy density of 4.976 J/cm. After the intervention, the patient was prohibited from smoking, using mouthwash, drinking, and brushing for two hours. The exact same procedure was repeated five and 10 days after the first intervention. Follow-up was made for three months after the intervention. The assessment indicated a minor increase in the papilla height, which was not enough for a complete closure of the "black triangle." However, there was a reduction in the appearance of the black triangle. This case report suggests that PBM if used within our suggested protocol can increase the height of the gingival interdental papilla leading to a more pleasant aesthetic appearance. It is important to note that its effectiveness might be limited to specific conditions. In summary, the presented case report showcased a slight extension of the gingival interdental papilla. Further studies are essential to validate these observations.

摘要

牙间乳头缺失,即所谓的“黑三角”,给美学修复带来了挑战。光生物调节疗法(PBMT)是一种非热光疗法,旨在积极调节生物活性,在组织再生、伤口愈合和减轻炎症方面已显示出前景。本病例报告介绍了一种改良的PBM方案,称为“血液激光疗法”,旨在使牙龈牙间乳头再生以填补黑三角。在本病例报告中,一名34岁女性因上颌中切牙之间存在不美观的黑三角前来就诊。在手术干预前,提出并解释了我们建议的方案,详细说明了潜在风险和结果。在进行适当的龈下刮治和根面平整后,制定了包含PBM的建议方案。使用波长为635nm的二极管激光在上颌两颗中切牙之间区域周围的四个点进行PBM治疗:乳头的冠方三分之一和根尖方三分之一以及乳头的近中侧和远中侧。然后,通过对结合上皮和龈上结缔组织施加压力,用刮匙在11和21(相关区域)之间的龈沟内引发出血。几秒钟后,血液自发充满牙间乳头冠方的“黑三角”且未受干扰。此时,再次在上述相同的四个点进行PBM治疗。所有PBM治疗期间的照射参数为接触模式和连续模式,波长635nm,光斑尺寸8mm,功率50mW,每个点的照射时间50秒,能量密度4.976J/cm。干预后,患者在两小时内禁止吸烟、使用漱口水、饮水和刷牙。在首次干预后的第5天和第10天重复完全相同的操作。干预后进行了三个月的随访。评估表明乳头高度略有增加,但不足以完全闭合“黑三角”。然而,黑三角的外观有所改善。本病例报告表明,如果按照我们建议的方案使用PBM,可以增加牙龈牙间乳头的高度,从而获得更美观的外观。需要注意的是,其有效性可能仅限于特定情况。总之,本病例报告展示了牙龈牙间乳头的轻微延长。进一步的研究对于验证这些观察结果至关重要。

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本文引用的文献

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Window therapeutic of extraoral photobiomodulation for prevention of oral mucositis in HSCT patients: additional arm.HSCT 患者口腔外光生物调节的窗治疗预防口腔黏膜炎:附加臂。
Support Care Cancer. 2023 Dec 15;32(1):27. doi: 10.1007/s00520-023-08243-y.
2
Effects of NGF and Photobiomodulation Therapy on Crush Nerve Injury and Fracture Healing: A Stereological and Histopathological Study in an Animal Model.神经生长因子和光生物调节疗法对挤压性神经损伤和骨折愈合的影响:动物模型的体视学和组织病理学研究
Craniomaxillofac Trauma Reconstr. 2023 Dec;16(4):281-291. doi: 10.1177/19433875221138175. Epub 2022 Nov 15.
3
Photobiomodulation Can Enhance Stem Cell Viability in Cochlea with Auditory Neuropathy but Does Not Restore Hearing.
光生物调节可增强听觉神经病模型耳蜗中干细胞的活力,但不能恢复听力。
Stem Cells Int. 2023 Nov 15;2023:6845571. doi: 10.1155/2023/6845571. eCollection 2023.
4
The implication of blue light-emitting diode on mesenchymal stem cells: a systematic review.蓝光二极管对间充质干细胞的影响:系统综述。
Lasers Med Sci. 2023 Nov 20;38(1):267. doi: 10.1007/s10103-023-03908-w.
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Blue light photobiomodulation for reactivation of healing in wounds not responding to standard therapy.蓝光光生物调节治疗对标准治疗无效的伤口愈合的再激活。
J Wound Care. 2023 Nov 2;32(11):695-703. doi: 10.12968/jowc.2023.32.11.695.
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Restoring black triangle with bioclear matrix versus conventional celluloid matrix method: a randomized clinical trial.采用 Bioclear 基质与传统赛璐珞基质方法修复黑三角:一项随机临床试验。
BMC Oral Health. 2023 Jun 17;23(1):402. doi: 10.1186/s12903-023-03102-y.
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Effectiveness of Hyaluronic Acid Gel Injection with and without PRGF for Management of Interdental Papillary Loss: A Randomized Clinical Trial.透明质酸凝胶注射联合或不联合富血小板纤维蛋白治疗牙龈乳头退缩的有效性:一项随机临床试验。
J Funct Biomater. 2023 Feb 18;14(2):114. doi: 10.3390/jfb14020114.
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Interproximal attachment gain: The challenge of periodontal regeneration.近中附着获得:牙周再生的挑战。
J Periodontol. 2021 Jul;92(7):931-946. doi: 10.1002/JPER.20-0587. Epub 2020 Nov 23.
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Photomed Laser Surg. 2018 Apr;36(4):221-226. doi: 10.1089/pho.2017.4349.