Department of Optics & Optometry & Vision Sciences, University of Valencia, C / Dr. Moliner, 50., 46100, Burjassot, Valencia, Spain.
ICARES Medicus, Inc, Hsinchu County, Taiwan.
Graefes Arch Clin Exp Ophthalmol. 2024 Aug;262(8):2541-2550. doi: 10.1007/s00417-024-06458-1. Epub 2024 Mar 25.
This study aimed to investigate the in vitro tolerance to decentration of biaspheric intraocular lens (IOLs) with refractive phase-ring extended depth-of-focus (EDOF) and diffractive trifocal designs.
This experimental study was carried out at the Department of Optics and Optometry and Vision Science, University of Valencia, Spain. The modulation transfer function (MTF) of the ETLIO130C EDOF and the TFLIO130C trifocal IOLs (AST Products Inc., Billerica, MA, USA) were determined at different levels of decentration for a given wavelength and pupil diameter using the PMTF optical bench (Lambda-X Ophthalmics, Nivelles, Belgium). The modulation transfer function (MTF) curves, the through-focus MTF curves, and the Strehl ratios were measured at 3-mm pupil aperture for 0.25-, 0.50- and 0.75-mm decentration.
The optical design of the trifocal TFLIO130C IOL is robust to small decentrations, with virtually no change in MTF response for 0.25 mm decentration. For greater decentration levels, the MTF response is slightly reduced with increasing decentration. The ETLIO130C EDOF design is robust to decentration, as the MTF response is only minimally affected when increasing the decentration up to 0.75 mm.
MTF responses are slightly reduced with greater levels of decentration, but the range of focus provided by both trifocal and EDOF designs are preserved. The effects for average levels of decentration reported in the literature are minimum for both IOL designs.
本研究旨在研究具有折射相位环扩展景深(EDOF)和衍射三焦点设计的双非球面人工晶状体(IOL)的体外离焦耐受性。
这项实验研究是在西班牙瓦伦西亚大学光学与验光和视觉科学系进行的。使用 PMTF 光学台(Lambda-X Ophthalmics,Nivelles,比利时),在给定波长和瞳孔直径下,确定 EDLIO130C EDOF 和 TFLIO130C 三焦点 IOL(AST Products Inc.,马萨诸塞州比勒里卡)在不同离焦水平下的调制传递函数(MTF)。在 3mm 瞳孔孔径下测量调制传递函数(MTF)曲线、聚焦 MTF 曲线和斯特列尔比,用于 0.25、0.50 和 0.75mm 的离焦。
三焦点 TFLIO130C IOL 的光学设计对小离焦具有鲁棒性,对于 0.25mm 的离焦,MTF 响应几乎没有变化。对于更大的离焦水平,随着离焦的增加,MTF 响应略有降低。EDLIO130C EDOF 设计对离焦具有鲁棒性,因为当离焦增加到 0.75mm 时,MTF 响应仅受到轻微影响。
随着离焦水平的增加,MTF 响应略有降低,但两种三焦点和 EDOF 设计提供的聚焦范围得以保留。对于文献中报道的平均离焦水平,两种 IOL 设计的影响最小。