Bratisl Lek Listy. 2024;125(4):250-257. doi: 10.4149/BLL_2024_38.
Insulin resistance (IR) is the most significant risk factor for post-transplant diabetes mellitus (PTDM). This study aimed to determine the effects of regular physical activity on IR and PTDM in patients after kidney transplantation (KT). The study group (n = 22) participated in aerobic or combined sports (aerobic and anaerobic). Monitoring was provided by a sports tracker (Xiaomi Mi Band 4, compatible with the Mi Fit mobile application). Waist circumference was significantly lower (p = 0.0437, p = 0.0372), graft function was better (p = 0.0036, p = 0.0137), fasting blood glucose was lower (p = 0.0016, p = 0.0003), C-peptide level was lower (p = 0.0447, p = 0014) in the 3rd and 6th months of monitoring, and low-density lipoprotein was lower at 6 months (p = 0.0444) in the observed group than in the control group. IR was significantly lower at 6 months (p = 0.0202), and fasting blood glucose was significantly lower at 3 and 6 months (p = 0.0227) in the observed group. We confirmed the significant effect of regular physical activity on preventing the development of IR and impaired fasting glucose levels in patients after KT (Tab. 1, Fig. 4, Ref. 27). Text in PDF www.elis.sk Keywords: kidney transplantation, insulin resistance, physical activity.
胰岛素抵抗（IR）是移植后糖尿病（PTDM）的最重要危险因素。本研究旨在确定有规律的体育活动对肾移植（KT）后患者的 IR 和 PTDM 的影响。研究组（n=22）参加了有氧运动或混合运动（有氧运动和无氧运动）。监测由运动追踪器（小米手环 4，与 Mi Fit 移动应用程序兼容）提供。腰围明显较低（p=0.0437，p=0.0372），移植物功能更好（p=0.0036，p=0.0137），空腹血糖较低（p=0.0016，p=0.0003），C 肽水平较低（p=0.0447，p=0.014）在第 3 和第 6 个月监测中，观察组的低密度脂蛋白在第 6 个月（p=0.0444）低于对照组。观察组在第 6 个月时 IR 明显降低（p=0.0202），空腹血糖在第 3 和第 6 个月时明显降低（p=0.0227）。我们证实了有规律的体育活动对预防 KT 后患者 IR 和空腹血糖水平受损的显著影响（表 1，图 4，参考文献 27）。
