Beijing Ditan Hospital Capital Medical University, Beijing, People's Republic of China.
National Center for AIDS/STD Control and Prevention, China CDC, Beijing, China.
AIDS Care. 2024 Jul;36(sup1):15-23. doi: 10.1080/09540121.2024.2332444. Epub 2024 Mar 25.
Mental health problems leads to serious disease burden among people living with HIV/AIDS (PLHIV). The study aimed at measuring the mental disorders-caused burden of disease based on PLHIV in mainland China. The data used was from the national HIV/AIDS case reporting system, life expectancy (LE) and LE-eliminated suicide were evaluated by the life-table method. The total YLLs and YLLs caused by suicide in each age group were calculated. The disability weights were estimated by the scale of depression symptoms (CES-D) from the multi-center cross-sectional survey, then calculated the corresponding YLDs as a burden of mental illness among PLHIV. Results showed that the LE had been prolonged by implementing antiviral therapy for PLHIV. The proportion of YLLs caused by suicide was the highest (5·46%) in the 15-24 age group. The YLDs in the 25-34 age group were the highest. The YLLs caused by suicide in males were higher than those in the same age group of females. The YLDs and YLLs were higher in heterosexual-infected PLHIV than in homosexual-infected PLHIV, except for YLLs in the 25-34 age group. In summary, this study first provided localized data on the disease burden caused by mental health problems among PLHIV.
心理健康问题导致 HIV/AIDS 感染者（PLHIV）的疾病负担严重。本研究旨在衡量中国大陆 PLHIV 中精神障碍疾病负担。使用的数据来自全国 HIV/AIDS 病例报告系统，采用寿命表法评估预期寿命（LE）和 LE 消除自杀。计算了每个年龄组的总 YLL 和自杀引起的 YLL。通过多中心横断面调查的抑郁症状量表（CES-D）评估残疾权重，然后计算相应的 YLD，作为 PLHIV 精神疾病负担。结果表明，实施抗病毒治疗延长了 PLHIV 的 LE。自杀引起的 YLLs 比例在 15-24 岁年龄组中最高（5.46%）。25-34 岁年龄组的 YLDs 最高。男性自杀引起的 YLLs 高于同年龄组的女性。除 25-34 岁年龄组外，异性恋感染的 PLHIV 的 YLDs 和 YLLs高于同性恋感染的 PLHIV。总之，本研究首次提供了 PLHIV 心理健康问题引起的疾病负担的本地化数据。
