Zare Ali, Bighamian Moein, Moloudi Farzad, Narouie Behzad, Rouientan Hamidreza
Department of Urology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Case Rep Oncol. 2024 Mar 25;17(1):484-489. doi: 10.1159/000538073. eCollection 2024 Jan-Dec.
Paraganglioma of the urinary bladder (PUB) is an extremely rare extra-adrenal catecholamine-secreting neuroendocrine tumor, accounting for only 0.05% of all bladder tumors and 1% of all pheochromocytomas. The clinical presentation of PUB can be diverse and challenging to diagnose.
This case report presents a 37-year-old man with post-micturition palpitation, headache, and sweating, with no history of hematuria or other irritative urinary symptoms. Ultrasound and contrast-enhanced computed tomography revealed a suspicious mass in the right posterolateral wall of the urinary bladder. Despite normal functional hormonal tests, the diagnosis of PUB was confirmed after surgical enucleation and histopathological examination.
This report emphasizes the importance of considering PUB as a differential diagnosis in patients with post-micturition symptoms and paroxysmal hypertension, as well as the need for a multidisciplinary approach in the evaluation and management of such rare and complex cases. Early recognition and surgical intervention are crucial for optimal management and favorable clinical outcomes.
膀胱副神经节瘤（PUB）是一种极其罕见的肾上腺外分泌儿茶酚胺的神经内分泌肿瘤，仅占所有膀胱肿瘤的0.05%和所有嗜铬细胞瘤的1%。PUB的临床表现多样，诊断具有挑战性。
本病例报告介绍了一名37岁男性，有排尿后心悸、头痛和出汗症状，无血尿或其他刺激性尿路症状病史。超声和增强计算机断层扫描显示膀胱右后壁有一个可疑肿块。尽管功能性激素检查正常，但手术摘除和组织病理学检查后确诊为PUB。
本报告强调了在有排尿后症状和阵发性高血压的患者中考虑PUB作为鉴别诊断的重要性，以及在评估和管理此类罕见复杂病例时采用多学科方法的必要性。早期识别和手术干预对于优化管理和取得良好临床结果至关重要。
