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高钠血症及其纠正速率:目前的证据

Hypernatremia and Its Rate of Correction: The Evidence So Far.

作者信息

Pokhriyal Sindhu C, Joshi Prachi, Gupta Uma, Roy Pulok, Parkash Sunil, Kunwar Kalendra, Al-Ghuraibawi Muthanna Mohammed Hasan, Nagpal Sagar, Yadav Ruchi, Panigrahi Kalpana

机构信息

Internal Medicine, Interfaith Medical Center, Brooklyn, USA.

Public Health, Georgia Southern University, Atlanta, USA.

出版信息

Cureus. 2024 Feb 22;16(2):e54699. doi: 10.7759/cureus.54699. eCollection 2024 Feb.

Abstract

Hypernatremia or high serum sodium levels can have many different causes, including insufficient free water intake, or excess free water losses. The management of hypernatremia focuses on resolving the underlying cause, replenishing free water deficit, and preventing further losses while closely monitoring serum sodium concentration. This systematic review was carried out using medical databases such as PubMed, PubMed Central, and Google Scholar for relevant medical literature. The identified articles were reviewed, eligibility criteria were applied, and seven research articles were identified. The effect of the rate of hypernatremia correction on both short- and long-term outcomes in volume-resuscitated patients was the focus of our search for randomized or observational studies. Based on our analysis of the clinical evidence, we concluded that the present recommendations for treating acute and chronic hypernatremia in resuscitated patients do not stem from high-quality research.

摘要

高钠血症或高血清钠水平可能有许多不同原因,包括自由水摄入不足或自由水丢失过多。高钠血症的管理重点在于解决潜在病因、补充自由水缺乏以及防止进一步丢失,同时密切监测血清钠浓度。本系统评价使用了如PubMed、PubMed Central和谷歌学术等医学数据库来检索相关医学文献。对检索到的文章进行了审查,应用了纳入标准,最终确定了7篇研究文章。我们检索随机对照或观察性研究的重点是高钠血症纠正速度对容量复苏患者短期和长期结局的影响。基于对临床证据的分析,我们得出结论,目前关于复苏患者急性和慢性高钠血症治疗的建议并非源于高质量研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9444/10961935/01407106444f/cureus-0016-00000054699-i01.jpg

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