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经 Palminteri-Ferrari 技术治疗的医源性或复发性膀胱颈挛缩:一种处理棘手情况的新方法。

Iatrogenic or recurrent bladder neck contracture treated by the Palminteri-Ferrari technique: a new way to approach a frustrating condition.

机构信息

Department of Urology, C.Ur.E., Centro Urologico Europeo, Hesperia Hospital, Via Arquà 80, Modena, Italy.

Department of Urology, University of Modena and Reggio Emilia, Modena, Italy.

出版信息

World J Urol. 2024 Mar 26;42(1):195. doi: 10.1007/s00345-024-04912-7.

Abstract

PURPOSE

Bladder neck stricture (BNS) is a bothersome disease which may affect patients after trauma or prostatic surgery. It is frustrating due to the low durable success rate of currently available surgical techniques. The aim of the study is to explore the efficacy of a novel technique.

MATERIALS & METHODS: The surgical protocol was developed by two high case-volume surgeons. The technique consists of Holmium laser incisions at 3-6-9-12 o'clock. Subsequently, triamcinolone acetonide 40 mg is injected. Two months later, the BNS is endoscopically checked in operatory room and re-procedure take place, if necessary (max 3 times). Failure was defined as the need of definitive urinary diversion. Subjective satisfaction was measured through PGI-I Questionnaire.

RESULTS

A total of 45 patients were enrolled. Median age was 63 (IQR 59-69) years and BNS developed by different causes. Naïve BNS procedure patients were 12 (26.7%), others 33 (73.3%) underwent median 2 (IQR 1-4) previous urethrotomies, including 16 other surgeries. Suprapubic bladder catheter was present in 34 patients (75.6%). No complications were registered. Re-procedure at control was necessary in 24 patients (53.3%) for a median of 1 (IQR 1-3) procedures. At median follow-up of 18 months, failures were 4 (8.9%) and urinary incontinence was reported in 2 patients (4.5%) who required incontinence surgery. Median PGI-I was 2.

CONCLUSIONS

Our technique of BNS treatment allows good outcomes and high rate of subjective improvement amongst patients. Moreover, naïve patients seem to have better results. However, longer follow-up and higher sample size are mandatory to further assess these data.

摘要

目的

膀胱颈部狭窄(BNS)是一种令人烦恼的疾病,可能会在创伤或前列腺手术后影响患者。由于目前可用的手术技术成功率低,因此令人沮丧。本研究的目的是探索一种新的技术。

材料和方法

该手术方案由两位高病例量的外科医生制定。该技术包括在 3-6-9-12 点钟方向进行钬激光切口,随后注射曲安奈德 40mg。两个月后,在手术室对 BNS 进行内镜检查,如果需要(最多 3 次),则进行重新治疗。失败的定义是需要永久性尿路改道。通过 PGI-I 问卷来衡量主观满意度。

结果

共纳入 45 例患者。中位年龄为 63 岁(IQR 59-69 岁),BNS 由不同原因引起。12 例(26.7%)为初次 BNS 手术患者,其余 33 例(73.3%)患者接受了中位 2 次(IQR 1-4 次)之前的尿道切开术,其中 16 例患者还接受了其他手术。34 例患者(75.6%)存在耻骨上膀胱导管。未发生任何并发症。24 例(53.3%)患者在控制时需要再次治疗,中位数为 1 次(IQR 1-3 次)。中位随访 18 个月时,4 例(8.9%)患者失败,2 例(4.5%)患者出现尿失禁,需要进行尿失禁手术。PGI-I 的中位数为 2。

结论

我们的 BNS 治疗技术可使患者获得良好的结果和较高的主观改善率。此外,初次患者似乎有更好的结果。然而,需要更长的随访和更大的样本量来进一步评估这些数据。

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