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远程医疗中心进行的远程随访在短期和长期内均能提高阻塞性睡眠呼吸暂停患者对持续气道正压通气(CPAP)的依从性。

Distance follow-up by a remote medical care centre improves adherence to CPAP in patients with obstructive sleep apnoea over the short and long term.

作者信息

Schisano Matteo, Libra Alessandro, Rizzo Ludovica, Morana Giorgio, Mancuso Salvatore, Ficili Antonella, Campagna Davide, Vancheri Carlo, Bonsignore Maria R, Spicuzza Lucia

机构信息

Respiratory Unit, University Hospital Policlinico- San Marco, Catania, Italy.

Respiratory Unit, Department of Translational Medicine, Sant'Anna University Hospital, Ferrara, Italy.

出版信息

J Telemed Telecare. 2024 Mar 27:1357633X241238483. doi: 10.1177/1357633X241238483.

Abstract

BACKGROUND

Adherence to continuous positive air pressure (CPAP) in patients with obstructive sleep apnoea (OSA) has remained invariably low over the last decades. Remote monitoring of the nocturnal CPAP treatment, within telemedicine (TM)-based follow-up programs, in these patients has been suggested as a potential tool to improve adherence and release the workload of sleep units. The aim of this study was therefore to assess whether a follow-up program carried out by a Remote Medical Care Centre (RMCC), outside the sleep unit, improves adherence to CPAP in the short and long term in patients with OSA.

METHODS

In this pilot protocol, we enrolled 37 patients starting CPAP in our Sleep Centre (SC). After three months of standard care in our SC, patients initiated a six-month remote follow-up carried out by the RMCC, functioning as an intermediary between patients and SC. Monthly reports and indication for face-to-face visits were sent to the SC for six months. After this period patients returned to usual care for one year. Results were compared with those obtained in 38 patients (controls) followed with usual care over the same time range.

RESULTS

Mean nightly use of CPAP increased from 3.2 ± 2.4 h pre-RMCC to 5.2 ± 1.9 h post-RMCC ( < 0.0001). Nights/month of CPAP use improved from 19.8 ± 9.2 to 25.2 ± 2.5 ( < 0.05) and nights/month with CPAP use >4 h from 12.5 ± 10 to 21.03 ± 8.9 ( < 0.05). This improvement remained stable after 12 months from the return of patients to usual care. No significant changes in CPAP use were observed in controls over the time.

CONCLUSION

A six-month follow-up through a remote facility can significantly improve adherence to CPAP in the short and long term. This pilot study provides a solid base for the design of multicentre randomized trials focusing on new models which are able to increase the long-term efficacy of TM programs.

摘要

背景

在过去几十年中,阻塞性睡眠呼吸暂停(OSA)患者对持续气道正压通气(CPAP)的依从性一直很低。在基于远程医疗(TM)的随访计划中,对这些患者夜间CPAP治疗进行远程监测,被认为是提高依从性和减轻睡眠单元工作量的潜在工具。因此,本研究的目的是评估由睡眠单元外的远程医疗中心(RMCC)开展的随访计划能否在短期和长期内提高OSA患者对CPAP的依从性。

方法

在本试点方案中,我们纳入了37名在我们睡眠中心(SC)开始使用CPAP的患者。在我们的SC进行三个月的标准护理后,患者开始由RMCC进行为期六个月的远程随访,RMCC充当患者与SC之间的中介。每月报告和面对面就诊指征会被发送至SC,持续六个月。在此期间过后,患者恢复常规护理一年。将结果与同期38名接受常规护理的患者(对照组)的结果进行比较。

结果

CPAP的平均每晚使用时间从RMCC干预前的3.2±2.4小时增加到RMCC干预后的5.2±1.9小时(<0.0001)。每月使用CPAP的天数从19.8±9.2天改善到25.2±2.5天(<0.05),每月使用CPAP>4小时的天数从12.5±10天增加到21.03±8.9天(<0.05)。在患者恢复常规护理12个月后,这种改善仍然稳定。在此期间,对照组的CPAP使用情况未观察到显著变化。

结论

通过远程机构进行的为期六个月的随访可以在短期和长期内显著提高对CPAP的依从性。这项试点研究为设计聚焦于能够提高TM计划长期疗效的新模型的多中心随机试验提供了坚实基础。

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