Khoeri Miftahuddin Majid, Maladan Yustinus, Salsabila Korrie, Alimsardjono Lindawati, Vermasari Naritha, Puspitasari Iva, Yunita Rina, Tafroji Wisnu, Sarassari Rosantia, Sari Ratna Fathma, Balqis Sarah Azhari, Wahid Ghina Athyah, Purwanto Diana Shinta, Harimurti Kuntjoro, Soebandrio Amin, Safari Dodi
Eijkman Research Center for Molecular Biology, National Research and Innovation Agency, Cibinong, West Java, Indonesia.
Doctoral program in Biomedical, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia.
Data Brief. 2024 Feb 27;53:110251. doi: 10.1016/j.dib.2024.110251. eCollection 2024 Apr.
is the leading cause of bacterial pneumonia, bacteremia, and meningitis. Indonesia introduced the pneumococcal conjugate vaccine (PCV) nationwide in 2022. In this study, we present whole genome sequence (WGS) data of 94 isolates that were obtained from hospitalized patients, healthy children, and adult groups from different regions prior to PCV program in Indonesia. DNA sequences of were obtained using the TruSeq Nano DNA kit (Illumina NovaSeq6000 Platform). The genome data of features a 1,969,562 bp to 2,741,371 bp circular chromosome with 39-40% G+C content. The genome includes 1935-3319 coding sequences (CDS), 2 to 5 rRNA genes, 43 to 49 tRNA genes, and 56 to 71 ncRNA. These data will be useful for analyzing the serotype, sequence type, virulence genes, antimicrobial resistance genes, and the impact of pneumococcal vaccination in Indonesia. The FASTQ raw files of these sequences are available under BioProject accession number PRJNA995903 and Sequence Read Archive accession numbers SRR25316461-SRR25316554.
是细菌性肺炎、菌血症和脑膜炎的主要病因。印度尼西亚于2022年在全国范围内引入了肺炎球菌结合疫苗(PCV)。在本研究中,我们展示了94株分离株的全基因组序列(WGS)数据,这些分离株是在印度尼西亚实施PCV计划之前,从不同地区的住院患者、健康儿童和成人组中获得的。使用TruSeq Nano DNA试剂盒(Illumina NovaSeq6000平台)获得 的DNA序列。 的基因组数据具有一条1,969,562 bp至2,741,371 bp的环状染色体,G+C含量为39-40%。该基因组包括1935-3319个编码序列(CDS)、2至5个rRNA基因、43至49个tRNA基因和56至71个非编码RNA。这些数据将有助于分析印度尼西亚肺炎球菌的血清型、序列类型、毒力基因、抗菌耐药基因以及肺炎球菌疫苗接种的影响。这些序列的FASTQ原始文件可在生物项目登录号PRJNA995903和序列读取存档登录号SRR25316461-SRR25316554下获取。