Bindlish Aabhas, Sawal Anupama
Anatomy, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus. 2024 Feb 25;16(2):e54855. doi: 10.7759/cureus.54855. eCollection 2024 Feb.
Breast cancer is a kind of aggressive cancer that significantly affects women worldwide, thus making research on alternative and new therapies necessary. The potential impact of bee venom on breast cancer is the main subject of this analysis of this research article. Bee venom has drawn the attention of the world with the help of its constituent ingredients, namely the bioactive compounds, enzymes, and complex blend of proteins. They have a particularly varied chemical makeup and proven anti-cancer capabilities. This is a detailed review demonstrating the components of bee venom and their individual functions in fighting cancer, as well as the results of previously conducted in-vitro and in-vivo research. As described later, bee venom has given positive results in triggering apoptosis, preventing cell migration, inhibiting metastasis and invasion, and suppressing the existing breast cancer cells. It is found to have worked better along with the already existing chemotherapy treatments. These results were also proved with the help of various animal studies that showed reduced tumor development, reduced metastasis, and improved therapeutic effectiveness. Furthermore, certain studies and case reports from all over the world have exhibited consistent results in females affected by breast cancer. This study found that people receiving chemotherapy experienced improved health outcomes and reduced discomfort, with fewer negative side effects. It is important to conduct extensive research on the safety and effectiveness of this treatment because it is yet to be approved. The ideal dosage and administration methods must be explored in clinical trials. Moreover, it is imperative to evaluate the results of any combined treatments with current medications. There should be constant monitoring to prevent any potential side effects. Other important things like allergic reactions and hidden concerns should also be considered.
乳腺癌是一种侵袭性癌症,对全球女性产生重大影响,因此有必要开展替代疗法和新疗法的研究。蜂毒对乳腺癌的潜在影响是本研究文章分析的主要主题。蜂毒借助其成分,即生物活性化合物、酶和复杂的蛋白质混合物,吸引了全世界的关注。它们具有特别多样的化学组成和已被证实的抗癌能力。这是一篇详细综述,展示了蜂毒的成分及其在抗癌中的各自功能,以及先前进行的体外和体内研究结果。如后文所述,蜂毒在引发细胞凋亡、阻止细胞迁移、抑制转移和侵袭以及抑制现有的乳腺癌细胞方面取得了积极成果。人们发现它与现有的化疗治疗配合使用效果更好。各种动物研究也证实了这些结果,这些研究表明肿瘤发展减缓、转移减少且治疗效果提高。此外,世界各地的某些研究和病例报告在乳腺癌女性患者中也呈现出一致的结果。该研究发现接受化疗的患者健康状况改善、不适减轻,副作用更少。由于这种治疗方法尚未获批,因此对其安全性和有效性进行广泛研究很重要。必须在临床试验中探索理想的剂量和给药方法。此外,评估与现有药物联合治疗的结果势在必行。应该持续监测以预防任何潜在的副作用。还应考虑其他重要事项,如过敏反应和潜在问题。