School of Public Health, Chongqing Medical University, Chongqing, China.
Research Center for Medicine and Social Development, Chongqing Medical University, Chongqing, China.
Public Health Nutr. 2024 Mar 27;27(1):e122. doi: 10.1017/S1368980024000703.
We aimed to examine the association between dietary Se intake and CVD risk in Chinese adults.
This prospective cohort study included adults above 20 years old in the China Health and Nutrition Survey (CHNS), and they were followed up from 1997 to 2015 ( 16 030). Dietary data were retrieved from CHNS, and a 3-d, 24-h recall of food intake was used to assess the cumulative average intake of dietary Se, which was divided into quartiles. The Cox proportional hazards model was adopted to analyse the association between dietary Se intake and incident CVD risk.
CHNS (1991, 1993, 1997, 2000, 2004, 2006, 2009, 2011 and 2015).
A total of 663 respondents developed CVD after being followed up for a mean of 9·9 years (median 9 years). The incidence of CVD was 4·3, 3·7, 4·6 and 4·0 per 1000 person-years across the quartiles of cumulative Se intake. After adjusting all potential factors, no significant associations were found between cumulative Se intake and CVD risk. No interactions were found between Se intake and income, urbanisation, sex, region, weight, hypertension and CVD risk.
We found no association between dietary Se and CVD.
我们旨在研究中国成年人膳食硒摄入与 CVD 风险之间的关联。
本前瞻性队列研究纳入了中国健康与营养调查（CHNS）中年龄在 20 岁以上的成年人，随访时间从 1997 年至 2015 年（共 16030 人）。膳食数据来自 CHNS，采用 3 天 24 小时回顾法评估膳食硒的累计平均摄入量，将其分为四分位。采用 Cox 比例风险模型分析膳食硒摄入与 CVD 发病风险之间的关联。
CHNS（1991 年、1993 年、1997 年、2000 年、2004 年、2006 年、2009 年、2011 年和 2015 年）。
共有 663 名受访者在平均 9.9 年（中位数为 9 年）的随访后发生 CVD。在累积硒摄入量四分位中，CVD 的发病率分别为每 1000 人年 4.3、3.7、4.6 和 4.0。在调整所有潜在因素后，累积硒摄入量与 CVD 风险之间没有显著关联。硒摄入量与收入、城市化程度、性别、地区、体重、高血压和 CVD 风险之间没有交互作用。
我们发现膳食硒与 CVD 之间没有关联。
