School of Chemical Engineering, Pusan National University, Busan 46241, Republic of Korea.
Department of Organic Material Science and Engineering, Pusan National University, Busan 46241, Republic of Korea.
Biosensors (Basel). 2024 Mar 7;14(3):137. doi: 10.3390/bios14030137.
Carbon nanotubes (CNTs) have been regarded as emerging materials in various applications. However, the range of biomedical applications is limited due to the aggregation and potential toxicity of powder-type CNTs. To overcome these issues, techniques to assemble them into various macroscopic structures, such as one-dimensional fibers, two-dimensional films, and three-dimensional aerogels, have been developed. Among them, carbon nanotube fiber (CNTF) is a one-dimensional aggregate of CNTs, which can be used to solve the potential toxicity problem of individual CNTs. Furthermore, since it has unique properties due to the one-dimensional nature of CNTs, CNTF has beneficial potential for biomedical applications. This review summarizes the biomedical applications using CNTF, such as the detection of biomolecules or signals for biosensors, strain sensors for wearable healthcare devices, and tissue engineering for regenerating human tissues. In addition, by considering the challenges and perspectives of CNTF for biomedical applications, the feasibility of CNTF in biomedical applications is discussed.
碳纳米管 (CNTs) 已被视为各种应用中的新兴材料。然而，由于粉末型 CNTs 的聚集和潜在毒性，其在生物医学应用中的范围受到限制。为了克服这些问题，已经开发了将它们组装成各种宏观结构的技术，例如一维纤维、二维薄膜和三维气凝胶。其中，碳纳米管纤维 (CNTF) 是 CNTs 的一维聚集体，可用于解决单个 CNTs 的潜在毒性问题。此外，由于 CNTs 的一维性质，CNTF 具有用于生物医学应用的有益潜力。本综述总结了使用 CNTF 的生物医学应用，例如用于生物传感器的生物分子或信号的检测、用于可穿戴医疗设备的应变传感器以及用于再生人体组织的组织工程。此外，通过考虑 CNTF 在生物医学应用中的挑战和观点，讨论了 CNTF 在生物医学应用中的可行性。
