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阴茎重建的组织工程学

Tissue Engineering for Penile Reconstruction.

作者信息

Elia Elissa, Caneparo Christophe, McMartin Catherine, Chabaud Stéphane, Bolduc Stéphane

机构信息

Centre de Recherche en Organogénèse Expérimentale/LOEX, Regenerative Medicine Division, CHU de Québec-Université Laval Research Center, Québec, QC G1J 1Z4, Canada.

Division of Urology, Department of Surgery, CHU de Québec-Université Laval, Québec, QC G1V 4G2, Canada.

出版信息

Bioengineering (Basel). 2024 Feb 28;11(3):230. doi: 10.3390/bioengineering11030230.

DOI:10.3390/bioengineering11030230
PMID:38534504
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10967839/
Abstract

The penis is a complex organ with a development cycle from the fetal stage to puberty. In addition, it may suffer from either congenital or acquired anomalies. Penile surgical reconstruction has been the center of interest for many researchers but is still challenging due to the complexity of its anatomy and functionality. In this review, penile anatomy, pathologies, and current treatments are described, including surgical techniques and tissue engineering approaches. The self-assembly technique currently applied is emphasized since it is considered promising for an adequate tissue-engineered penile reconstructed substitute.

摘要

阴茎是一个从胎儿期到青春期具有发育周期的复杂器官。此外,它可能会出现先天性或后天性异常。阴茎手术重建一直是许多研究人员关注的焦点,但由于其解剖结构和功能的复杂性,仍然具有挑战性。在这篇综述中,描述了阴茎的解剖结构、病理状况和当前的治疗方法,包括手术技术和组织工程方法。由于目前应用的自组装技术被认为在构建合适的组织工程阴茎替代物方面很有前景,因此对其进行了重点介绍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8a2/10967839/c2f4bff673c1/bioengineering-11-00230-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8a2/10967839/89976c71033c/bioengineering-11-00230-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8a2/10967839/c55b78a9f00a/bioengineering-11-00230-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8a2/10967839/7a9371b5a191/bioengineering-11-00230-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8a2/10967839/b50ae44c4f89/bioengineering-11-00230-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8a2/10967839/1ea3538a8583/bioengineering-11-00230-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8a2/10967839/32052cc2541a/bioengineering-11-00230-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8a2/10967839/c2f4bff673c1/bioengineering-11-00230-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8a2/10967839/89976c71033c/bioengineering-11-00230-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8a2/10967839/c55b78a9f00a/bioengineering-11-00230-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8a2/10967839/7a9371b5a191/bioengineering-11-00230-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8a2/10967839/b50ae44c4f89/bioengineering-11-00230-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8a2/10967839/1ea3538a8583/bioengineering-11-00230-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8a2/10967839/32052cc2541a/bioengineering-11-00230-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8a2/10967839/c2f4bff673c1/bioengineering-11-00230-g007.jpg

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Engineered human organ-specific urethra as a functional substitute.工程化的人源器官特异性尿道作为功能性替代品。
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