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从床边到便携式和可穿戴式:用于深层乳房组织成像的贴合式超声贴片的开发。

From bedside to portable and wearable: development of a conformable ultrasound patch for deep breast tissue imaging.

机构信息

Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Department of Radiology, Breast Imaging Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

出版信息

Mol Oncol. 2023 Oct;17(10):1947-1949. doi: 10.1002/1878-0261.13531. Epub 2023 Oct 3.

Abstract

A breakthrough study from Du et al. has developed a wearable, ultrasound imaging patch for standardized and reproducible breast tissue imaging. The technology utilizes a honeycomb patch design to facilitate guided movement of the ultrasound array, enabling comprehensive, multiangle breast imaging. The system was validated in vitro and in vivo with a single human subject and has the potential for early-stage breast cancer detection. This study addressed the current limitations of wearable ultrasound technologies, including imaging over large, curvilinear organs and integration of superior piezoelectric materials for high-performance ultrasound arrays. The transition of ultrasound from the bedside to portable and wearable devices will pave the way for integration with big data collection, such as artificial intelligence (AI)-based diagnosis and personalized ultrasonographic profile generation, for rapid and objective measurements. This advancement is especially important in the context of breast cancer, where early diagnosis and assessment of medical therapy responses are paramount to patient care.

摘要

段玉友等人的突破性研究开发出一种可穿戴式超声成像贴片,可实现标准化和可重复的乳腺组织成像。该技术利用蜂窝状贴片设计来促进超声阵列的引导运动,从而实现全面、多角度的乳腺成像。该系统已在体外和体内的单个人体对象中进行了验证,具有早期乳腺癌检测的潜力。这项研究解决了当前可穿戴式超声技术的局限性,包括对大的、曲线器官的成像以及用于高性能超声阵列的卓越压电材料的集成。超声技术将从床边向便携式和可穿戴设备的转变将为与大数据采集(如基于人工智能的诊断和个性化超声特征生成)的集成铺平道路,以便快速、客观的测量。这一进展在乳腺癌领域尤为重要,因为早期诊断和评估医学治疗反应对患者护理至关重要。

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本文引用的文献

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Automated Breast Ultrasound Screening for Dense Breasts.自动乳腺超声筛查致密乳腺。
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A Quantitative Ultrasound-Based Multi-Parameter Classifier for Breast Masses.基于定量超声的乳腺肿块多参数分类器。
Ultrasound Med Biol. 2019 Jul;45(7):1603-1616. doi: 10.1016/j.ultrasmedbio.2019.02.025. Epub 2019 Apr 26.
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Piezoelectric Biomaterials for Sensors and Actuators.压电生物材料用于传感器和执行器。
Adv Mater. 2019 Jan;31(1):e1802084. doi: 10.1002/adma.201802084. Epub 2018 Oct 8.
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Ultrasound Imaging Technologies for Breast Cancer Detection and Management: A Review.用于乳腺癌检测与管理的超声成像技术:综述
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