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用于神经组织修复的可注射水凝胶——简要综述

Injectable Hydrogels for Nervous Tissue Repair-A Brief Review.

作者信息

Politrón-Zepeda Gladys Arline, Fletes-Vargas Gabriela, Rodríguez-Rodríguez Rogelio

机构信息

Ingeniería en Sistemas Biológicos, Centro Universitario de los Valles (CUVALLES), Universidad de Guadalajara, Carretera Guadalajara-Ameca Km. 45.5, Ameca 46600, Jalisco, Mexico.

Departamento de Ciencias Clínicas, Centro Universitario de los Altos (CUALTOS), Universidad de Guadalajara, Carretera Tepatitlán-Yahualica de González Gallo, Tepatitlán de Morelos 47620, Jalisco, Mexico.

出版信息

Gels. 2024 Mar 9;10(3):190. doi: 10.3390/gels10030190.

Abstract

The repair of nervous tissue is a critical research field in tissue engineering because of the degenerative process in the injured nervous system. In this review, we summarize the progress of injectable hydrogels using in vitro and in vivo studies for the regeneration and repair of nervous tissue. Traditional treatments have not been favorable for patients, as they are invasive and inefficient; therefore, injectable hydrogels are promising for the treatment of damaged tissue. This review will contribute to a better understanding of injectable hydrogels as potential scaffolds and drug delivery system for neural tissue engineering applications.

摘要

由于受损神经系统的退行性过程,神经组织修复是组织工程中的一个关键研究领域。在本综述中,我们总结了可注射水凝胶在体外和体内用于神经组织再生与修复研究的进展。传统治疗方法对患者不利,因为它们具有侵入性且效率低下;因此,可注射水凝胶在受损组织治疗方面具有广阔前景。本综述将有助于更好地理解可注射水凝胶作为神经组织工程应用潜在支架和药物递送系统的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a683/10970171/a08d05c01b6b/gels-10-00190-g001.jpg

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