Benković Maja, Laljak Izvorka, Valinger Davor, Jurina Tamara, Sokač Cvetnić Tea, Gajdoš Kljusurić Jasenka, Jurinjak Tušek Ana
Faculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, 10000 Zagreb, Croatia.
Gels. 2024 Mar 16;10(3):201. doi: 10.3390/gels10030201.
The aim of this work was to analyze and compare the adsorption and desorption processes of carbohydrates (glucose as a model molecule), polyphenols (gallic acid as a model molecule), and proteins (bovine serum albumin, BSA as a model molecule) on alginate microcapsules. The adsorption and desorption processes were described by mathematical models (pseudo-first-order, pseudo-second-order, and Weber-Morris intraparticle diffusion model for adsorption, and first-order, Korsmeyer-Peppas, and the Higuchi model for desorption) in order to determine the dominant mechanisms responsible for both processes. By comparing the values of adsorption rate () and initial adsorption rate () based on the pseudo-first-order model, the lowest values were recorded for BSA ( = 0.124 ± 0.030 min), followed by glucose ( = 0.203 ± 0.041 min), while the model-obtained values for gallic acid were not considered significant at < 0.05. For glucose and gallic acid, the limiting step of the adsorption process is the chemical sorption of substances, and the rate of adsorption does not depend on the adsorbate concentration, but depends on the capacity of the hydrogel adsorbent. Based on the desorption rates determined by the Korsmeyer-Peppas model (), the highest values were recorded for gallic acid ( = 3.66236 ± 0.20776 g beads/mg gallic acid per min), followed by glucose ( = 2.55760 ± 0.16960 g beads/mg glucose per min) and BSA ( = 0.78881 ± 0.11872 g beads/mg BSA per min). The desorption process from alginate hydrogel microcapsules is characterized by the pseudo Fickian diffusion mechanism.
这项工作的目的是分析和比较碳水化合物（以葡萄糖为模型分子）、多酚（以没食子酸为模型分子）和蛋白质（牛血清白蛋白，以BSA为模型分子）在藻酸盐微胶囊上的吸附和解吸过程。通过数学模型（吸附的伪一级、伪二级和韦伯-莫里斯颗粒内扩散模型，以及解吸的一级、科尔斯梅耶-佩帕斯和 Higuchi 模型）描述吸附和解吸过程，以确定这两个过程的主要机制。基于伪一级模型比较吸附速率（）和初始吸附速率（）的值，BSA 的值最低（ = 0.124 ± 0.030 min），其次是葡萄糖（ = 0.203 ± 0.041 min），而没食子酸的模型获得值在 < 0.05 时不被认为显著。对于葡萄糖和没食子酸，吸附过程的限速步骤是物质的化学吸附，吸附速率不取决于吸附质浓度，而是取决于水凝胶吸附剂的容量。基于科尔斯梅耶-佩帕斯模型确定的解吸速率（），没食子酸的值最高（ = 3.66236 ± 0.20776 g 珠子/毫克没食子酸每分钟），其次是葡萄糖（ = 2.55760 ± 0.16960 g 珠子/毫克葡萄糖每分钟）和 BSA（ = 0.78881 ± 0.11872 g 珠子/毫克 BSA 每分钟）。藻酸盐水凝胶微胶囊的解吸过程以伪菲克扩散机制为特征。
