“靶向放射性核素治疗放射性药物设计中的分子生物学”特刊社论
Editorial for the Special Issue "Molecular Biology in Targeted Radionuclide Therapy Radiopharmaceutical Design".
作者信息
Aprile Carlo, Geatti Onelio, Canziani Letizia, Lodola Lorenzo
机构信息
Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Studio di Radiologia Bazzocchi, 34135 Trieste, Italy.
出版信息
Curr Issues Mol Biol. 2024 Mar 13;46(3):2398-2401. doi: 10.3390/cimb46030152.
Abstract
Targeted radionuclide therapy (TRT) is gaining wide and rapid acceptance in clinical practice as it can deliver alpha or beta irradiation to a tumor-associated target which may be present in the tumor cell itself or in the microenvironment [...].
摘要
靶向放射性核素治疗（TRT）在临床实践中正在迅速得到广泛认可，因为它可以将α或β辐射传递到肿瘤相关靶点，该靶点可能存在于肿瘤细胞本身或微环境中[...]。
相似文献
1
Editorial for the Special Issue "Molecular Biology in Targeted Radionuclide Therapy Radiopharmaceutical Design".“靶向放射性核素治疗放射性药物设计中的分子生物学”特刊社论
Curr Issues Mol Biol. 2024 Mar 13;46(3):2398-2401. doi: 10.3390/cimb46030152.
2
Pb Theranostic Radiopharmaceuticals for Image-guided Radionuclide Therapy for Cancer.用于癌症导向放射性核素治疗的放射性诊断和治疗药剂。
Curr Med Chem. 2020;27(41):7003-7031. doi: 10.2174/0929867327999200727190423.
3
Combining Targeted Radionuclide Therapy and Immune Checkpoint Inhibition for Cancer Treatment.联合靶向放射性核素治疗和免疫检查点抑制治疗癌症。
Clin Cancer Res. 2022 Sep 1;28(17):3652-3657. doi: 10.1158/1078-0432.CCR-21-4332.
4
A Mathematical Modeling Approach for Targeted Radionuclide and Chimeric Antigen Receptor T Cell Combination Therapy.一种用于靶向放射性核素与嵌合抗原受体T细胞联合治疗的数学建模方法。
Cancers (Basel). 2021 Oct 15;13(20):5171. doi: 10.3390/cancers13205171.
5
Integrin αβ-targeted radionuclide therapy combined with immune checkpoint blockade immunotherapy synergistically enhances anti-tumor efficacy.整合素 αβ 靶向放射性核素治疗联合免疫检查点阻断免疫治疗协同增强抗肿瘤疗效。
Theranostics. 2019 Oct 16;9(25):7948-7960. doi: 10.7150/thno.39203. eCollection 2019.
6
Solid-tumor radionuclide therapy dosimetry: new paradigms in view of tumor microenvironment and angiogenesis.实体瘤放射性核素治疗剂量学：基于肿瘤微环境和血管生成的新范例。
Med Phys. 2010 Jun;37(6):2974-84. doi: 10.1118/1.3431999.
7
Optimizing the Safety and Efficacy of Bio-Radiopharmaceuticals for Cancer Therapy.优化用于癌症治疗的生物放射性药物的安全性和有效性。
Pharmaceutics. 2023 Apr 30;15(5):1378. doi: 10.3390/pharmaceutics15051378.
8
Targeted α-Therapy Using Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment.使用锕放射性标记的单域抗体进行靶向α治疗可诱导抗原特异性免疫反应，并在全身和肿瘤微环境中发挥免疫调节作用。
J Nucl Med. 2023 May;64(5):751-758. doi: 10.2967/jnumed.122.264752. Epub 2023 Apr 13.
9
Antitumor efficacy of Y-NM600 targeted radionuclide therapy and PD-1 blockade is limited by regulatory T cells in murine prostate tumors.Y-NM600 靶向放射性核素治疗和 PD-1 阻断的抗肿瘤疗效受小鼠前列腺肿瘤中调节性 T 细胞的限制。
J Immunother Cancer. 2022 Aug;10(8). doi: 10.1136/jitc-2022-005060.
10
Targeted radionuclide therapy directed to the tumor phenotypes: A dosimetric approach using MC simulations.针对肿瘤表型的靶向放射性核素治疗：一种使用蒙特卡罗模拟的剂量学方法。
Appl Radiat Isot. 2023 Feb;192:110569. doi: 10.1016/j.apradiso.2022.110569. Epub 2022 Nov 19.
本文引用的文献
1
Diagnostic and Therapeutic Radiopharmaceuticals: A "Hot" Topic.诊断与治疗用放射性药物：一个“热门”话题。
J Med Chem. 2023 Dec 28;66(24):16457-16463. doi: 10.1021/acs.jmedchem.3c02281. Epub 2023 Dec 18.
2
Nuclear Medicine and Cancer Theragnostics: Basic Concepts.核医学与癌症诊疗学：基本概念
Diagnostics (Basel). 2023 Sep 26;13(19):3064. doi: 10.3390/diagnostics13193064.
3
Molecular imaging for better theranostics.用于更好的诊疗一体化的分子成像
Eur J Nucl Med Mol Imaging. 2023 Nov;50(13):3799-3801. doi: 10.1007/s00259-023-06415-w.
4
Diagnosis, Management and Theragnostic Approach of Gastro-Entero-Pancreatic Neuroendocrine Neoplasms.胃肠胰神经内分泌肿瘤的诊断、管理及诊疗一体化方法
Cancers (Basel). 2023 Jul 4;15(13):3483. doi: 10.3390/cancers15133483.
5
Theranostics and Patient-Specific Dosimetry.治疗诊断学和患者特定剂量学。
Semin Radiat Oncol. 2023 Jul;33(3):317-326. doi: 10.1016/j.semradonc.2023.03.011.
6
Molecular basis and targeted therapy in thyroid cancer: Progress and opportunities.甲状腺癌的分子基础与靶向治疗：进展与机遇。
Biochim Biophys Acta Rev Cancer. 2023 Jul;1878(4):188928. doi: 10.1016/j.bbcan.2023.188928. Epub 2023 May 29.
7
State of the Art in the Current Management and Future Directions of Targeted Therapy for Differentiated Thyroid Cancer.分化型甲状腺癌靶向治疗的现状与未来方向
Int J Mol Sci. 2022 Mar 23;23(7):3470. doi: 10.3390/ijms23073470.
8
Novel Peptide Therapeutic Approaches for Cancer Treatment.新型肽类癌症治疗疗法。
Cells. 2021 Oct 27;10(11):2908. doi: 10.3390/cells10112908.
9
Artificial Intelligence and the Future of Diagnostic and Therapeutic Radiopharmaceutical Development:: In Silico Smart Molecular Design.人工智能与诊断和治疗放射性药物开发的未来：计算机辅助智能分子设计。
PET Clin. 2021 Oct;16(4):513-523. doi: 10.1016/j.cpet.2021.06.008. Epub 2021 Aug 5.
10
General Concepts in Theranostics.治疗诊断学的一般概念。
PET Clin. 2021 Jul;16(3):313-326. doi: 10.1016/j.cpet.2021.03.010.
Zotero 插件