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一例血清学确诊的产后莱姆病罕见病例,其孕期感染无症状且未发生子宫内垂直传播。

An Unusual Case of Serologically Confirmed Post-Partum Lyme Disease Following an Asymptomatic Infection Acquired during Pregnancy and Lacking Vertical Transmission in Utero.

作者信息

Pavia Charles S, Plummer Maria M, Varantsova Alena

机构信息

Department of Biomedical Sciences, New York Institute of Technology, College of Osteopathic Medicine, Old Westbury, NY 11568, USA.

Division of Infectious Diseases, New York Medical College, Valhalla, NY 10595, USA.

出版信息

Pathogens. 2024 Feb 20;13(3):186. doi: 10.3390/pathogens13030186.

Abstract

In this report, we describe a 23-year-old female who, while pregnant, was exposed to but did not develop significant signs or symptoms (joint pain, arthritis) of Lyme disease until shortly after delivering a healthy child at term. Serologic testing confirmed infection with . A 3-week course of treatment with doxycycline was completely curative. There was no evidence for congenital or perinatal transmission of this pathogen at any point pre-term or postnatally. The key reasons that could account for this unique clinical scenario are discussed in the context of previously published related reports.

摘要

在本报告中,我们描述了一名23岁的女性,她在怀孕期间接触了[病原体名称未给出],但直到足月产下一名健康婴儿后不久才出现莱姆病的显著体征或症状(关节疼痛、关节炎)。血清学检测证实感染了[病原体名称未给出]。给予多西环素为期3周的治疗后完全治愈。在早产或产后的任何时间点均无该病原体先天性或围产期传播的证据。结合先前发表的相关报告,讨论了可能导致这一独特临床情况的关键原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60d3/10976031/110861290063/pathogens-13-00186-g001.jpg

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