Sun Yuelong, Zhang Mengjie, Shi Dongdong, Dai Xiaofeng, Li Xiumei
Key Laboratory of Feed Biotechnology, Ministry of Agriculture and Rural Affairs, Institute of Feed Research of CAAS, Beijing 100081, China.
Vet Sci. 2024 Feb 29;11(3):107. doi: 10.3390/vetsci11030107.
The objective of this study was to investigate the effect of the designed herbal formula (DHF) on growth performance, blood indices, organ traits, and cecum microbiology in broilers. A total of 96 male broilers of 1 d were selected and randomly assigned to two groups with six replicates of eight broilers each. The control (CON) and the basal diet containing 1.0% DHF (, Koidz., Linnaeus, and , 2:1:1:2) were fed separately. The experiment was conducted for 35 days. The results showed that the DHF diet increased body weight and decreased the feed conversion ratio (FCR) ( < 0.05). At 21 days, the spleen, thymus, lymphocytes, and thrombocytes were increased ( < 0.05), and pancreas, duodenum, heterophils, and mean corpuscular hemoglobin (MCH) were decreased ( < 0.05). At 35 days, the heart, pancreas, white blood cell, heterophils, hemoglobin, MCH and mean corpuscular hemoglobin concentration (MCHC) were decreased, while lymphocytes and middle cells were increased ( < 0.05). The results of microbial diversity analysis showed that the DHF diet decreased the microbial diversity of the cecum. Firmicutes and Bacteroidetes were the dominant phyla, where the DHF diet increased the relative abundances of , , and , and then decreased the relative abundance of . In conclusion, DHF played a positive role in improving the growth performance, immune performance, and relative abundance of , , and in cecum microbiology in broilers, and has the potential to be used as a novel feed additive.
本研究的目的是探讨设计的草药配方（DHF）对肉鸡生长性能、血液指标、器官特征和盲肠微生物学的影响。总共选择了96只1日龄的雄性肉鸡，随机分为两组，每组8只肉鸡，共六个重复。分别饲喂对照组（CON）和含有1.0% DHF（，小檗科，林奈，以及，2:1:1:2）的基础日粮。实验进行了35天。结果表明，DHF日粮增加了体重，降低了饲料转化率（FCR）（<0.05）。在21日龄时，脾脏、胸腺、淋巴细胞和血小板增加（<0.05），而胰腺、十二指肠、嗜异性粒细胞和平均红细胞血红蛋白（MCH）减少（<0.05）。在35日龄时，心脏、胰腺、白细胞、嗜异性粒细胞、血红蛋白、MCH和平均红细胞血红蛋白浓度（MCHC）降低，而淋巴细胞和中间细胞增加（<0.05）。微生物多样性分析结果表明，DHF日粮降低了盲肠的微生物多样性。厚壁菌门和拟杆菌门是主要的门类，其中DHF日粮增加了、和的相对丰度，然后降低了的相对丰度。总之，DHF在提高肉鸡生长性能、免疫性能以及盲肠微生物学中、和的相对丰度方面发挥了积极作用，并且有潜力用作新型饲料添加剂。
