HDGFL2 隐秘蛋白报告神经退行性疾病中 TDP-43 病理学的存在。
HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases.
机构信息
Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
Neurobiology of Disease Graduate Program, Mayo Graduate School, Mayo Clinic College of Medicine, Rochester, MN, USA.
出版信息
Mol Neurodegener. 2024 Mar 27;19(1):29. doi: 10.1186/s13024-024-00718-8.
Abstract
This letter demonstrates the potential of novel cryptic proteins resulting from TAR DNA-binding protein 43 (TDP-43) dysfunction as markers of TDP-43 pathology in neurodegenerative diseases.
摘要
这封信证明了新型隐秘蛋白的潜力，这些蛋白源自 TAR DNA 结合蛋白 43（TDP-43）功能障碍，可作为神经退行性疾病中 TDP-43 病理学的标志物。
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