幼儿使用磷酸盐灌肠剂的风险：危及生命的未被重视情况。
The Risks of Phosphate Enemas in Toddlers: A Life-Threatening Unawareness.
作者信息
Zago Alessandro, Occhipinti Alessandro Agostino, Bramuzzo Matteo, Ceconi Viola, Colacino Vincenzo, Barbi Egidio, Poropat Federico
机构信息
Department of Medicine, Surgery and Health Sciences, University of Trieste, 34149 Trieste, Italy.
Department of Pediatrics, Institute for Maternal and Child Health-IRCCS "Burlo Garofolo", 34137 Trieste, Italy.
出版信息
Children (Basel). 2024 Mar 15;11(3):349. doi: 10.3390/children11030349.
BACKGROUND
While oral laxatives represent the first-line treatment of fecal impaction, enemas are frequently used in clinical practice in pediatric emergency departments (PEDs) and by family pediatricians (FPs).
OBJECTIVES
Phosphate-containing enemas (PcEs) are commonly employed, even causing the risk of rare but lethal toxicity. We investigated pediatricians' awareness of PcE risks.
METHODS
We conducted an online survey by sending a multiple-choice questionnaire to the referents of 51 PEDs and 101 FPs. We collected and compared the answers with recommendations reported by the Italian Drug Agency (AIFA) and the available literature about PcE administration.
RESULTS
Of the institutions and pediatricians receiving the questionnaire, 23 PEDs (45%) and 63 FP (62.3%) participated in the survey. Of PEDs, 95% and 33.0% of FPs treated fecal impaction with PcE. Moreover, 54% of PEDs and 86.0% of FPs did not provide treatment according to the AIFA recommendations for the daily dose.
CONCLUSIONS
This study shows limited pediatricians' awareness of the potential risks related to PcE.
背景
虽然口服泻药是粪便嵌塞的一线治疗方法，但灌肠剂在儿科急诊科（PEDs）和家庭儿科医生（FPs）的临床实践中经常使用。
目的
含磷酸盐灌肠剂（PcEs）被普遍使用，甚至会导致罕见但致命的毒性风险。我们调查了儿科医生对PcE风险的认知情况。
方法
我们通过向51个儿科急诊科和101位家庭儿科医生的负责人发送多项选择题问卷进行了一项在线调查。我们收集了答案并与意大利药品管理局（AIFA）报告的建议以及有关PcE给药的现有文献进行了比较。
结果
在收到问卷的机构和儿科医生中，23个儿科急诊科（45%）和63位家庭儿科医生（62.3%）参与了调查。在儿科急诊科中, 95%的医生和33.0%的家庭儿科医生使用PcE治疗粪便嵌塞。此外，54%的儿科急诊科和86.0%的家庭儿科医生未按照AIFA的每日剂量建议进行治疗。
结论
这项研究表明儿科医生对与PcE相关的潜在风险的认知有限。
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