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卵巢恶性勃勒纳瘤：文献系统综述

Malignant Brenner Tumor of the Ovary: A Systematic Review of the Literature.

作者信息

Koufopoulos Nektarios I, Pouliakis Abraham, Samaras Menelaos G, Kotanidis Christakis, Boutas Ioannis, Kontogeorgi Adamantia, Dimas Dionysios, Sitara Kyparissia, Zacharatou Andriani, Ieronimaki Argyro-Ioanna, Spathis Aris, Leventakou Danai, Zanelli Magda, Pateras Ioannis S, Panayiotides Ioannis G, Palicelli Andrea, Syrios John

机构信息

Second Department of Pathology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, 12462 Athens, Greece.

Breast Unit, Rea Maternity Hospital, 17564 Athens, Greece.

出版信息

Cancers (Basel). 2024 Mar 9;16(6):1106. doi: 10.3390/cancers16061106.

DOI:10.3390/cancers16061106
PMID:38539441
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10968811/
Abstract

BACKGROUND

Malignant Brenner tumors are rare ovarian tumors, accounting for less than 1% of malignant ovarian neoplasms. The aim of this manuscript is to systematically review the current literature concerning malignant Brenner tumors.

METHODS

We searched three medical databases (PubMed, Scopus, and Web of Science) for relevant articles published until 15 September 2023.

RESULTS

After applying inclusion and exclusion criteria, 48 manuscripts describing 115 cases were included in this study from the English literature.

CONCLUSIONS

We analyzed the demographic, clinical, pathological, and oncological characteristics of 115 patients with malignant Brenner tumors. The statistical analysis showed that recurrence was marginally statistically significantly related to tumor stage and was more common in patients with ascites and in women with abnormal CA-125 levels; patients that were treated with lymphadenectomy had better disease-specific survival.

摘要

背景

恶性勃勒纳瘤是罕见的卵巢肿瘤，占恶性卵巢肿瘤的比例不到1%。本文的目的是系统回顾有关恶性勃勒纳瘤的当前文献。

方法

我们在三个医学数据库（PubMed、Scopus和科学网）中检索截至2023年9月15日发表的相关文章。

结果

应用纳入和排除标准后，本研究从英文文献中纳入了48篇描述115例病例的手稿。

结论

我们分析了115例恶性勃勒纳瘤患者的人口统计学、临床、病理和肿瘤学特征。统计分析表明，复发与肿瘤分期在统计学上有微弱的显著相关性，在有腹水的患者和CA-125水平异常的女性中更常见；接受淋巴结清扫术治疗的患者有更好的疾病特异性生存率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f1f/10968811/b63b1618b075/cancers-16-01106-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f1f/10968811/7c9dbdfa88a4/cancers-16-01106-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f1f/10968811/c10ee2512407/cancers-16-01106-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f1f/10968811/b63b1618b075/cancers-16-01106-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f1f/10968811/7c9dbdfa88a4/cancers-16-01106-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f1f/10968811/c10ee2512407/cancers-16-01106-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f1f/10968811/b63b1618b075/cancers-16-01106-g003.jpg

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Coexistence of malignant ovarian Brenner tumor and borderline mucinous cystadenoma, combined with primary uterine corpus endometrioid carcinoma: A case report and literature review.
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Oncol Lett. 2022 Jun 22;24(2):272. doi: 10.3892/ol.2022.13392. eCollection 2022 Aug.
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