Yüksel Dilek, Kılıç Ciğdem, Çakır Caner, Kimyon Cömert Günsu, Turan Taner, Ünlübilgin Eylem, Boran Nurettin, Kayıkçıoğlu Fulya, Koç Sevgi
Clinic of Gynecologic Oncology, University of Health Sciences Turkey, Etlik Zübeyde Hanım Women’s Health Teaching and Research Hospital, Ankara, Turkey
Clinic of Gynecology and Obstetrics, University of Health Sciences Turkey, Etlik Zübeyde Hanım Women’s Health Teaching and Research Hospital, Ankara, Turkey
J Turk Ger Gynecol Assoc. 2022 Mar 8;23(1):22-27. doi: 10.4274/jtgga.galenos.2021.2021.0001. Epub 2022 Jan 10.
The purpose of the present study was to evaluate the clinical and pathological features and oncological outcomes of Brenner tumors (BT).
Evaluation was performed on the data of 46 patients with BTs retrieved from the oncology clinic database and pathology reports between 2005 and 2020.
The median (range) age of the patients was 52 (22-75) years. Median (range) tumor size was 52.5 (5.0-300) mm. The tumor was benign in 37 (80.4%), borderline in one (2.2%), and malignant in the remaining eight (17.4%). Ten (21.7%) of the tumors were detected incidentally. Mixed tumor, BT plus another ovarian pathology, was found in 13 (28.2%). Recurrence developed in 2/8 (25%) with malignant BT (MBT). The stage of these patients was 3C, and both received chemotherapy after surgery.
BTs are rare and generally detected incidentally. MBTs are treated in the same way as epithelial tumors. Due to the rarity of these tumors, lymphadenectomy and optimal chemotherapy regimens are controversial issues.
本研究旨在评估勃勒纳瘤（BT）的临床和病理特征以及肿瘤学结局。
对2005年至2020年间从肿瘤门诊数据库和病理报告中检索出的46例BT患者的数据进行评估。
患者的中位（范围）年龄为52（22 - 75）岁。中位（范围）肿瘤大小为52.5（5.0 - 300）mm。37例（80.4%）肿瘤为良性，1例（2.2%）为交界性，其余8例（17.4%）为恶性。10例（21.7%）肿瘤为偶然发现。13例（28.2%）发现混合性肿瘤，即BT合并另一种卵巢病变。2/8例（25%）恶性BT（MBT）出现复发。这些患者的分期为3C期，均在手术后接受了化疗。
BT罕见，通常为偶然发现。MBT的治疗方式与上皮性肿瘤相同。由于这些肿瘤罕见，淋巴结清扫术和最佳化疗方案存在争议。
