Institute of Special Wild Economic Animals and Plants, Chinese Academy of Agricultural Sciences, Changchun 130112, China.
Jilin Provincial Key Laboratory of Traditional Chinese Medicinal Materials Cultivation and Propagation, Changchun 130112, China.
Molecules. 2024 Mar 20;29(6):1379. doi: 10.3390/molecules29061379.
The rhizomes of the genus DC. consist of various bioactive components, including sesquiterpenes, which have attracted a great deal of research interest in recent years. In the present study, we reviewed the previously published literatures prior to November 2023 on the chemical structures, biosynthetic pathways, and pharmacological activities of the sesquiterpenoids from this genus via online databases such as Web of Science, Google Scholar, and ScienceDirect. Phytochemical studies have led to the identification of more than 160 sesquiterpenes, notably eudesmane-type sesquiterpenes. Many pharmacological activities have been demonstrated, particularly anticancer, anti-inflammatory, and antibacterial and antiviral activities. This review presents updated, comprehensive and categorized information on the phytochemistry and pharmacology of sesquiterpenes in DC., with the aim of offering guidance for the future exploitation and utilization of active ingredients in this genus.
DC.属的根茎含有多种生物活性成分，包括倍半萜，近年来引起了广泛的研究兴趣。本研究通过 Web of Science、Google Scholar 和 ScienceDirect 等在线数据库，对截至 2023 年 11 月之前发表的有关该属倍半萜的化学结构、生物合成途径和药理活性的文献进行了综述。植物化学研究已鉴定出 160 多种倍半萜，其中以艾里莫芬烷型倍半萜为主。许多药理活性已得到证实，特别是抗癌、抗炎、抗菌和抗病毒活性。本综述提供了关于 DC.属倍半萜的植物化学和药理学的最新、全面和分类信息，旨在为该属中活性成分的未来开发和利用提供指导。
