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复发性脑膜瘤患者中侵袭性胸膜血管外皮细胞瘤/孤立性纤维性肿瘤的意外发现:一例报告

An Unexpected Finding of an Aggressive Pleural Hemangiopericytoma/Solitary Fibrous Tumor in a Patient With Recurrent Meningioma: A Case Report.

作者信息

Basir Shahir, Bosiers Jana, van Walree Nico C

机构信息

Respiratory Medicine, Antwerp University Hospital, Antwerp, BEL.

Respiratory Medicine, Amphia Hospital, Breda, NLD.

出版信息

Cureus. 2024 Feb 26;16(2):e54965. doi: 10.7759/cureus.54965. eCollection 2024 Feb.

Abstract

Pleural hemangiopericytoma/solitary fibrous tumor (HPC/SFT) is a rare form of mesenchymal tumor arising from pericytes, which predominantly occurs intrathoracically. HPC/SFT can be suspected on imaging, but radiographic features are non-specific. Therefore, histological confirmation remains the gold standard. Due to the rarity of the tumor, specific anatomical pathological expertise is necessary to make the diagnosis, which is not available in every hospital. Here, we report the case of a 51-year-old female with a medical history of recurrent meningiomas. A chest CT scan revealed extensive subpleural soft tissue lesions in the left hemithorax with histological characteristics suggestive of a pleural malignancy. A specialized analysis of the sample led to the final diagnosis of HPC/SFT. Unfortunately, in the meantime, the patient's condition worsened rapidly, and she passed away before the final diagnosis was made and any decisions about therapeutic options were taken. In our case, we want to highlight the importance of having knowledge about the existence of this type of tumor in order to make the correct diagnosis in a timely manner.

摘要

胸膜血管外皮细胞瘤/孤立性纤维性肿瘤(HPC/SFT)是一种罕见的间叶组织肿瘤,起源于周细胞,主要发生于胸腔内。HPC/SFT在影像学上可被怀疑,但影像学特征不具有特异性。因此,组织学确诊仍是金标准。由于该肿瘤罕见,做出诊断需要特定的解剖病理学专业知识,而并非每家医院都具备。在此,我们报告一例51岁女性病例,其有复发性脑膜瘤病史。胸部CT扫描显示左半胸广泛的胸膜下软组织病变,组织学特征提示胸膜恶性肿瘤。对样本进行的专业分析最终确诊为HPC/SFT。不幸的是,在此期间,患者病情迅速恶化,在做出最终诊断并就治疗方案做出任何决定之前去世。在我们的病例中,我们想强调了解这类肿瘤存在的重要性,以便及时做出正确诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af8a/10971482/5e7331a0f3c0/cureus-0016-00000054965-i01.jpg

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