一组负责酿酒酵母中尿囊素降解的三个基因。
A cluster of three genes responsible for allantoin degradation in Saccharomyces cerevisiae.
作者信息
Cooper T G, Gorski M, Turoscy V
出版信息
Genetics. 1979 Jun;92(2):383-96. doi: 10.1093/genetics/92.2.383.
Abstract
Mutant strains of Saccharomyces cerevisiae unable to utilize allantoin as sole nitrogen source were isolated and divided into three groups on the basis of their biochemical and genetic characteristics. The three loci associated with these mutant classes were designated dal1 (allantoinase minus), dal2 (allantoicase minus) and dal4 (allantoin transport minus). All three loci are located in a cluster that is proximal to the lys1 locus on the right arm of chromosome IX. The gene order and intergenic distances were estimated to be: dal1--2.5 cM--dal4--1.9cM--dal2--4.6cM-lys1.
摘要
分离出了不能将尿囊素作为唯一氮源利用的酿酒酵母突变菌株，并根据其生化和遗传特性将其分为三组。与这些突变类别相关的三个基因座分别命名为dal1（尿囊素酶缺陷型）、dal2（尿囊酸酶缺陷型）和dal4（尿囊素转运缺陷型）。所有这三个基因座都位于一个簇中，该簇靠近第九条染色体右臂上的lys1基因座。基因顺序和基因间距离估计为：dal1--2.5厘摩--dal4--1.9厘摩--dal2--4.6厘摩--lys1。
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