Barber Nathaniel, Freud Lindsay
The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
CJC Pediatr Congenit Heart Dis. 2023 Nov 4;3(1):33-42. doi: 10.1016/j.cjcpc.2023.10.012. eCollection 2024 Feb.
The field of fetal cardiology has evolved significantly in recent years. This review focuses on specific advances in fetal cardiac imaging and intervention that are increasingly used in clinical practice. On the imaging frontier, updated screening guidelines and artificial intelligence hold promise for improving prenatal detection of congenital heart disease. Advances in ultrasound technology and magnetic resonance imaging techniques have enabled greater diagnostic and prognostic accuracy of fetal heart disease from the first to third trimesters, and maternal hyperoxygenation can offer additional physiological insights. Fetal cardiac therapy has also seen great progress, with advances in transplacental pharmacologic treatments, infusions of enzyme replacement therapy, and fetal surgery for select rare and severe conditions.
近年来,胎儿心脏病学领域取得了显著进展。本综述重点关注胎儿心脏成像和干预方面的具体进展,这些进展在临床实践中的应用越来越广泛。在成像前沿,更新的筛查指南和人工智能有望提高先天性心脏病的产前检测率。超声技术和磁共振成像技术的进步使从孕早期到孕晚期对胎儿心脏病的诊断和预后准确性更高,母体高氧可提供更多生理见解。胎儿心脏治疗也取得了巨大进展,包括经胎盘药物治疗、酶替代疗法输注以及针对某些罕见和严重病症的胎儿手术。