Suppr超能文献

手足部骨巨细胞瘤的治疗

Management of Giant Cell Tumors in Hand and Foot.

作者信息

Ulucaköy Coşkun, Atalay İsmail Burak, Öztürk Recep, Yapar Aliekber, Karakoç Yaman

机构信息

Department of Orthopaedics and Traumatology, Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Demetevler Mahallesi, Vatan Cad., 06200 Yenimahalle, Ankara Turkey.

出版信息

Indian J Surg Oncol. 2024 Mar;15(Suppl 1):86-93. doi: 10.1007/s13193-020-01153-z. Epub 2020 Aug 1.

Abstract

The aim of this study is to determine the treatment modalities and clinical characteristics of 12 patients diagnosed with giant cell tumor (GCT) of the hand and foot. The clinical findings, treatment modalities, and treatment failures of 12 patients with giant cell tumors of the hand and foot bones between 2007 and 2018 years were evaluated retrospectively. The average age at diagnosis was 29.2 ± 14.9 std. (between 16 and 62 years old), 8 males (66.6%) and 4 females (33.3%). Tumor was more frequently located in the talus, metacarpal, and metatarsal bones. The mean tumor size was 3.1 ± 1.1 cm (between 2.2 and 5.3 cm). The mean post-operative follow-up period was 76.3 ± 42.5 (between 12 and 139 months). The most of patients' (58.3%) common complaints were pain. The most commonly used surgical method was curettage + autografting (91.7%). Infection was seen in one patient after relapse surgery. Recurrence occurred in 33.3% of the patients in the first year. Only one patient was detected to have knee and lung metastases. Swelling and pain in the hand and foot should be examined for tumor lesions. When a bone lesion is detected, the giant cell tumor of the bone should be included in the differential diagnosis. Patients with giant cell tumors should be followed closely for recurrence and metastasis after treatment.

摘要

本研究的目的是确定12例被诊断为手足骨巨细胞瘤(GCT)患者的治疗方式及临床特征。回顾性评估了2007年至2018年间12例手足骨巨细胞瘤患者的临床表现、治疗方式及治疗失败情况。诊断时的平均年龄为29.2±14.9标准差(16至62岁),男性8例(66.6%),女性4例(33.3%)。肿瘤更常见于距骨、掌骨和跖骨。肿瘤平均大小为3.1±1.1厘米(2.2至5.3厘米)。术后平均随访期为76.3±42.5(12至139个月)。大多数患者(58.3%)的常见主诉是疼痛。最常用的手术方法是刮除术+自体骨移植(91.7%)。1例患者复发手术后出现感染。33.3%的患者在第一年复发。仅1例患者被检测出有膝关节和肺部转移。对于手足部肿胀和疼痛应检查是否存在肿瘤病变。当检测到骨病变时,骨巨细胞瘤应列入鉴别诊断。骨巨细胞瘤患者治疗后应密切随访有无复发和转移。

相似文献

1
Management of Giant Cell Tumors in Hand and Foot.手足部骨巨细胞瘤的治疗
Indian J Surg Oncol. 2024 Mar;15(Suppl 1):86-93. doi: 10.1007/s13193-020-01153-z. Epub 2020 Aug 1.
3
A Rare Case of Giant-Cell Tumor of Hand in a Young Male.一名年轻男性手部巨细胞瘤的罕见病例。
Cureus. 2022 Jan 19;14(1):e21408. doi: 10.7759/cureus.21408. eCollection 2022 Jan.
5
Giant cell tumor of the bones of the hand and foot.手足骨巨细胞瘤
Cancer. 2000 May 1;88(9):2022-32. doi: 10.1002/(sici)1097-0142(20000501)88:9<2022::aid-cncr6>3.0.co;2-y.
6
Giant Cell Tumor of Talus - A Case Report.距骨巨细胞瘤——病例报告
J Orthop Case Rep. 2022 Oct;12(10):87-90. doi: 10.13107/jocr.2022.v12.i10.3380.
8
Giant Cell Tumor of Talus: A Case Report.距骨巨细胞瘤:一例报告
J Orthop Case Rep. 2022 Sep;12(9):92-94. doi: 10.13107/jocr.2022.v12.i09.3332.
9
Giant cell tumor of bone in the foot and ankle.足踝部骨巨细胞瘤
Foot Ankle Int. 1995 Oct;16(10):617-23. doi: 10.1177/107110079501601007.

本文引用的文献

1
Inoperable Sacral Giant Cell Tumor: Therapeutic Options and Pain Control.不可切除的骶骨巨细胞瘤:治疗选择与疼痛控制
Rev Bras Ortop (Sao Paulo). 2019 May;54(3):347-352. doi: 10.1055/s-0039-1692450. Epub 2019 Jun 27.
2
Giant cell tumor of the small bones of the foot.足部小骨巨细胞瘤
J Orthop Surg (Hong Kong). 2018 May-Aug;26(3):2309499018801168. doi: 10.1177/2309499018801168.
4
Primary tumors of the spine: a review of clinical features in 438 patients.脊柱原发性肿瘤:438例患者临床特征回顾
J Neurooncol. 2015 Feb;121(3):513-20. doi: 10.1007/s11060-014-1650-8. Epub 2015 Feb 1.
8
A clinicopathological study of giant cell tumor of small bones.小骨巨细胞瘤的临床病理研究。
Ups J Med Sci. 2011 Nov;116(4):265-8. doi: 10.3109/03009734.2011.596290. Epub 2011 Sep 16.
10
Case 122: giant cell tumor of the second metatarsal.
Radiology. 2007 Oct;245(1):288-91. doi: 10.1148/radiol.2451031776.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验