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含有柠檬桉叶提取物的壳聚糖/聚乙烯吡咯烷酮可生物降解抗菌薄膜的制备

Fabrication of biodegradable and antibacterial films of chitosan/polyvinylpyrrolidone containing Eucalyptus citriodora extracts.

作者信息

Aldalbahi Ali, Thamer Badr M, Abdulhameed Meera Moydeen, El-Newehy Mohamed H

机构信息

Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.

Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.

出版信息

Int J Biol Macromol. 2024 May;266(Pt 2):131001. doi: 10.1016/j.ijbiomac.2024.131001. Epub 2024 Mar 26.

Abstract

The main objective of this work is to develop biodegradable active films through the combination of the extracts with different solvents sourced from Eucalyptus citriodora leaves, with films made of chitosan (Cs) and polyvinylpyrrolidone (PVP). Chromatographic profiling investigations were carried out to examine the antibacterial characteristics of E. citriodora extracts before their direct incorporation into the polymer films. At this point, the potent antimicrobial properties of the phenol compounds and bioactive components demonstrated an antibacterial activity that was particularly noticeable at a hexane resolution. Different morphological characteristics were seen on films made from these solvent extracts, such as Cs/PVP-AE, Cs/PVP-EAE, and Cs/PVP-HE, when scanning electron microscopy was used. Numerous other outcomes of all the interactions between the extract particles and the film were shown by the pores defined by the Cs/PVP film's porous nature. The addition of the extracts, either alone or in combination, greatly enhanced the Cs/NC/PVP films' mechanical characteristics. It has also been shown that adding plant extracts greatly increased the antibacterial activity of these films. These findings reveal that Cs/PVP films loaded with extract may be utilized as more environmentally acceptable substitutes for possible food packaging application by increasing shelf life of food products.

摘要

这项工作的主要目标是通过将源自柠檬桉树叶的不同溶剂提取物与壳聚糖(Cs)和聚乙烯吡咯烷酮(PVP)制成的薄膜相结合,开发可生物降解的活性薄膜。在将柠檬桉提取物直接掺入聚合物薄膜之前,进行了色谱分析研究以检查其抗菌特性。此时,酚类化合物和生物活性成分的强效抗菌性能表现出抗菌活性,在己烷分辨率下尤为明显。当使用扫描电子显微镜时,由这些溶剂提取物制成的薄膜,如Cs/PVP-AE、Cs/PVP-EAE和Cs/PVP-HE,呈现出不同的形态特征。Cs/PVP薄膜的多孔性质所界定的孔隙显示了提取物颗粒与薄膜之间所有相互作用的许多其他结果。单独或组合添加提取物极大地增强了Cs/NC/PVP薄膜的机械性能。研究还表明,添加植物提取物大大提高了这些薄膜的抗菌活性。这些发现表明,负载提取物的Cs/PVP薄膜通过延长食品保质期,可作为食品包装应用中更环保的替代品。

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