Center of Bioimmobilisation and Innovative Packaging Materials, Faculty of Food Sciences and Fisheries, West Pomeranian University of Technology in Szczecin, Janickiego 35, 71-270 Szczecin, Poland.
Center for Nanotechnology Research and Education, Department of Microbiology and Biotechnology, Faculty of Biotechnology and Animal Husbandry, West Pomeranian University of Technology in Szczecin, Piastów Avenue 45, 70-311 Szczecin, Poland.
Int J Mol Sci. 2021 Dec 14;22(24):13438. doi: 10.3390/ijms222413438.
Low density polyethylene (LDPE) films covered with active coatings containing mixtures of rosemary, raspberry, and pomegranate CO extracts were found to be active against selected bacterial strains that may extend the shelf life of food products. The coatings also offer antiviral activity, due to their influence on the activity of Φ6 bacteriophage, selected as a surrogate for SARS-CoV-2 particles. The mixture of these extracts could be incorporated into a polymer matrix to obtain a foil with antibacterial and antiviral properties. The initial goal of this work was to obtain active LDPE films containing a mixture of CO extracts of the aforementioned plants, incorporated into an LDPE matrix via an extrusion process. The second aim of this study was to demonstrate the antibacterial properties of the active films against Gram-positive and Gram-negative bacteria, and to determine the antiviral effect of the modified material on Φ6 bacteriophage. In addition, an analysis was made on the influence of the active mixture on the polymer physicochemical features, e.g., mechanical and thermal properties, as well as its color and transparency. The results of this research indicated that the LDPE film containing a mixture of raspberry, rosemary, and pomegranate CO extracts incorporated into an LDPE matrix inhibited the growth of . This film was also found to be active against . This modified film did not inhibit the growth of and cells; however, their number decreased significantly. The LDPE active film was also found to be active against Φ6 particles, meaning that the film had antiviral properties. The incorporation of the mixture of CO extracts into the polymer matrix affected its mechanical properties. It was observed that parameters describing mechanical properties decreased, although did not affect the transition of LDPE significantly. Additionally, the modified film exhibited barrier properties towards UV radiation. Modified PE/CO extracts films could be applied as a functional food packaging material with antibacterial and antiviral properties.
低密度聚乙烯(LDPE)薄膜覆盖有活性涂层,其中包含迷迭香、覆盆子和石榴 CO 提取物的混合物,被发现对可能延长食品保质期的选定细菌菌株具有活性。由于其对 Φ6 噬菌体活性的影响,这些涂层还具有抗病毒活性,Φ6 噬菌体被选为 SARS-CoV-2 颗粒的替代物。可以将这些提取物的混合物掺入聚合物基质中,以获得具有抗菌和抗病毒特性的箔。这项工作的最初目标是获得含有上述植物的 CO 提取物混合物的活性 LDPE 薄膜,通过挤出工艺将其掺入 LDPE 基质中。本研究的第二个目的是证明活性薄膜对革兰氏阳性和革兰氏阴性细菌的抗菌特性,并确定改性材料对 Φ6 噬菌体的抗病毒作用。此外,还对活性混合物对聚合物物理化学特性(例如机械和热性能以及颜色和透明度)的影响进行了分析。研究结果表明,含有迷迭香、覆盆子和石榴 CO 提取物混合物的 LDPE 薄膜掺入 LDPE 基质中抑制了 的生长。该薄膜还对 表现出活性。这种改性薄膜不会抑制 和 细胞的生长,但它们的数量明显减少。活性 LDPE 薄膜还对 Φ6 颗粒表现出活性,这意味着该薄膜具有抗病毒特性。将 CO 提取物混合物掺入聚合物基质会影响其机械性能。观察到描述机械性能的参数降低,但对 LDPE 的转变没有明显影响。此外,改性薄膜对紫外线辐射表现出阻隔性能。改性 PE/CO 提取物薄膜可用作具有抗菌和抗病毒特性的功能性食品包装材料。