Department of Medicine, Kaiser Permanente San Francisco Medical Center, 2425 Geary Boulevard, San Francisco, CA 94115, USA.
Department of Cardiology, Kaiser Permanente San Francisco Medical Center, 2425 Geary Boulevard, San Francisco, CA 94115, USA.
Med Clin North Am. 2024 May;108(3):553-566. doi: 10.1016/j.mcna.2023.11.007. Epub 2023 Dec 18.
Ischemic cardiomyopathy (ICM) is the most common underlying etiology of heart failure in the United States and is a significant contributor to deaths due to cardiovascular disease worldwide. The diagnosis and management of ICM has advanced significantly over the past few decades, and the evidence for medical therapy in ICM is both compelling and robust. This contrasts with evidence for coronary revascularization, which is more controversial and favors surgical approaches. This review will examine landmark clinical trial results in detail as well as provide a comprehensive overview of the current epidemiology, diagnostic approaches, and management strategies of ICM.
缺血性心肌病（ICM）是美国心力衰竭最常见的潜在病因，也是全球心血管疾病死亡的主要原因。在过去几十年中，ICM 的诊断和管理取得了重大进展，ICM 药物治疗的证据既令人信服又强大。这与冠状动脉血运重建形成对比，后者更具争议性，并且倾向于采用手术方法。本综述将详细探讨标志性临床试验结果，并全面概述 ICM 的当前流行病学、诊断方法和管理策略。
