低阿普加评分在大型单中心队列中识别短期病态新生儿的作用。
The contribution of low Apgar scores in identifying neonates with short-term morbidities in a large single center cohort.
机构信息
School of Medicine, Virginia Commonwealth University, Children's Hospital of Richmond at VCU, Richmond, VA, USA.
Division of Neonatal Medicine, Children's Hospital of Richmond at VCU, Richmond, VA, USA.
出版信息
J Perinatol. 2024 Jun;44(6):865-872. doi: 10.1038/s41372-024-01944-0. Epub 2024 Mar 28.
OBJECTIVE
To evaluate the association and utility of low 1- and 5-min Apgar scores to identify short-term morbidities in a large newborn cohort.
METHODS
15,542 infants >22 weeks gestation from a single center were included. Clinical data and low Apgar scores were analyzed for significance to ten short-term outcomes and were used to construct Receiver Operating Characteristic Curves and the AUC calculated for ten outcomes.
RESULTS
A low Apgar score related to all (1-min) or most (5-min) outcomes by univariate and multivariate logistic regression analysis. Including any of the 4 low Apgar scores only improved the clinical factor AUC by 0.9% ± 2.7% (±SD) and was significant in just 5 of the 40 score/outcome scenarios.
CONCLUSION
The contribution of a low Apgar score for identifying risk of short-term morbidity does not appear to be clinically significant.
目的
评估低 1 分钟和 5 分钟 Apgar 评分与识别大新生儿队列短期发病率的关联和效用。
方法
纳入了来自单个中心的 15542 名胎龄超过 22 周的婴儿。分析临床数据和低 Apgar 评分与 10 种短期结局的相关性，并用于构建受试者工作特征曲线，计算 10 种结局的 AUC。
结果
单变量和多变量逻辑回归分析表明，低 Apgar 评分与所有（1 分钟）或大多数（5 分钟）结局相关。仅包括任何 4 个低 Apgar 评分仅使临床因素 AUC 提高了 0.9%±2.7%（±标准差），并且仅在 40 个评分/结局场景中的 5 个中具有统计学意义。
结论
低 Apgar 评分对于识别短期发病率风险的贡献似乎没有临床意义。
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