Faculty of Kinesiology, University of Zagreb, Zagreb, Croatia.
Department of Pharmacology, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.
Acta Clin Croat. 2023 Aug;62(2):330-338. doi: 10.20471/acc.2023.62.02.11.
The incidence of diabetes is increasing worldwide, emphasizing an emerging need for blood glucose control optimization to prevent the development of chronic complications and improve the quality of life. This retrospective cohort study aimed to investigate the effects of total physical activity on microvascular diabetic complication development in patients with type 1 diabetes mellitus (T1DM). The study included 71 T1DM patients, average age 41 years and HbA1c 7.78%. Most patients (82.1%) reported having hypoglycemia, while the minority of patients developed microvascular complications, mostly nonproliferative retinopathy (17.7%). All subjects included in the study were moderately or vigorously physically active. No association was observed between total physical activity and regulation of glycemia, hypoglycemic incidents, or development of microvascular complications. Until sufficient data from prospective studies become available, our data support the findings of no negative effect of higher intensity physical activity on the development of microvascular complications in T1DM patients.
糖尿病的发病率在全球范围内不断增加，这强调了优化血糖控制以预防慢性并发症和提高生活质量的迫切需求。本回顾性队列研究旨在探讨总身体活动对 1 型糖尿病（T1DM）患者微血管糖尿病并发症发展的影响。该研究纳入了 71 名 T1DM 患者，平均年龄 41 岁，糖化血红蛋白（HbA1c）为 7.78%。大多数患者（82.1%）报告有低血糖，而少数患者出现了微血管并发症，主要是非增殖性视网膜病变（17.7%）。研究中所有受试者均为中度或剧烈体力活动。总身体活动与血糖调节、低血糖事件或微血管并发症的发展之间未观察到关联。在有足够的前瞻性研究数据之前，我们的数据支持高强度体力活动对 T1DM 患者微血管并发症发展没有负面影响的发现。
